Stavia Tablet 100 mg (Sitagliptin Phosphate Hydrate)

Adult dose

For adult patients, this medication is administered once daily at a dose of 100 mg, with a maximum daily dose of 100 mg. This medication can be taken with or without food. For patients with renal impairment, dosage adjustments are necessary based on renal function. - Mild renal impairment (eGFR 60-90 mL/min/1.73 m2): No dose adjustment necessary. - Moderate renal impairment (eGFR 45-60 mL/min/1.73 m2):

This medication may cause severe allergic reactions in some patients; therefore, if symptoms such as skin rash or difficulty breathing occur, stop taking it immediately and consult a doctor. This medication can induce acute pancreatitis, a severe inflammation of the pancreas; hence, any symptoms such as abdominal pain, nausea, or vomiting should prompt immediate medical attention. Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication, and those allergic to this medication or its components should avoid it. Patients with reduced kidney function need dose adjustments for this medication, thus regular kidney function tests should be conducted, and the drug should be taken according to the doctor's instructions. In clinical trials, adverse effects have been reported, primarily upper respiratory infections, nasopharyngitis, and headaches, and the risk of hypoglycemia may increase when used in combination with other diabetes medications, so caution is needed. When taking this medication with insulin or sulfonylurea, hypoglycemic symptoms may occur, hence blood sugar should be checked frequently, and dose adjustments may be necessary. If severe joint pain or skin blistering symptoms occur, the use of this medication should be stopped immediately, and medical staff should be informed. Pregnant or nursing women are advised against using this medication, and safety in children or adolescents under 18 has not been established. Elderly patients may experience decreased kidney function; therefore, kidney function should be regularly evaluated before and after taking this medication. In the case of overdose, general treatment measures should be followed, and dialysis may be considered if necessary, so strict adherence to the prescribed dosages is crucial. This medication has relatively few drug interactions, but it should be taken according to doctor's instructions when used with cyclosporine or digoxin. If unusual symptoms arise while taking this medication, inform medical staff immediately to receive appropriate measures.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, severe hypersensitivity reactions such as anaphylaxis, Stevens-Johnson syndrome, and exfoliative skin diseases, severe rashes with fever, blisters, skin peeling, oral/ocular mucosal pain, severe cutaneous adverse reactions, acute pancreatitis, severe liver abnormalities (jaundice), sudden and severe headaches, confusion, visual disturbances, paralysis, and other serious neurological symptoms.

Mild side effects

• Upper respiratory infections
• nasopharyngitis
• constipation
• vomiting
• headaches
• joint pain
• muscle pain
• limb pain
• back pain
• itching

This medication should be stored in a tightly sealed container that is air-tight and best kept at ambient temperatures between 1 to 30 degrees Celsius. This way, the medication's effectiveness will be well maintained and degradation prevented.

Appearance

Beige, round, biconvex film-coated tablet

Package unit

28 tablets/box [(14 tablets/PTPX2)]