Specaject 250 mg (Gefitinib)

Adult dose

Adults: Take 1 tablet orally once daily. This medicine may be taken with or without food at approximately the same time each day. Swallow the tablet whole with water. If the tablet cannot be swallowed whole, it may be dispersed in water (non-carbonated water) before administration. Do not use any other beverage. Without crushing the tablet, place it in half a glass of drinking water and stir occasionally until it disperses (up to 20 minutes); drink immediately once dispersion is complete. Rinse the glass with half a glass of water and drink. The dispersion may also be administered through a nasogastric tube or gastrostomy tube.

This drug is used for the treatment of non-small cell lung cancer. Before administration, patients must be fully informed about the effects, safety, and potential unusual symptoms such as shortness of breath. This drug can cause a serious lung disease called interstitial lung disease, and caution is particularly necessary during initial administration. If symptoms such as shortness of breath, cough, or fever occur, administration should be stopped immediately and healthcare professionals should be consulted. Thorough examinations are required before administering this drug to patients with dangerous lung diseases such as acute lung failure or interstitial pneumonia, and it should be administered with great caution in such cases. This drug should only be used in medical institutions with experienced doctors and the capability to respond to emergencies. Patients with a previous allergic reaction to any component of this drug, nursing mothers, and genetically lactose intolerant patients should not be administered this drug. Patients with poor liver function or severe liver impairment and patients with severe kidney impairment should be administered this drug with caution, and regular liver function tests should be conducted during treatment. While taking this drug, various side effects such as diarrhea, skin rashes, vomiting, and liver function abnormalities may occur, so symptoms should be closely monitored. In particular, if pulmonary symptoms or ocular abnormalities occur, immediate consultation with a physician is required, and treatment may be discontinued if such side effects are severe. The safety and efficacy of this drug have not been established when used in combination with other anticancer agents or radiation therapy, so it should be used alone. There may be interactions with acid suppressants, certain antibiotics, antifungals, and the like during treatment, so consultation with a doctor or pharmacist is necessary when using these medications together. Women who are pregnant or may become pregnant should receive proper counseling on risks before taking this drug, and its use should be avoided during nursing. There are no indications for children or adolescents, and it can be administered to the elderly without special dosage adjustments, but careful monitoring is needed. If a dose is missed, take it as soon as possible, but skip it if the next dose is near, and do not take double doses. This drug must be taken by removing the packaged tablets; taking it in its packaged state can lead to serious side effects such as esophageal damage. Store out of reach of children, and do not transfer to another container for safety.

Shortness of breath, interstitial lung disease, cough, fever, diarrhea, skin reactions (rash, acne, dry skin, pruritus), loss of appetite, conjunctivitis, keratitis, dry eye, corneal inflammation, corneal ulcer, abnormal eyelash growth, nosebleed, hematuria, vomiting, nausea, stomatitis, dehydration, dry mouth, pancreatitis, gastrointestinal perforation, increased ALT, increased AST, elevated total bilirubin, hepatitis, pustular rash, nail and hair abnormalities, alopecia, angioedema, urticaria, palmoplantar erythrodysesthesia syndrome, blisters, toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiforme, cutaneous vasculitis, increased serum creatinine, proteinuria, cystitis, hemorrhagic cystitis, asthenia, fever, asymptomatic increase in serum creatinine, fever, pain, weakness, fatigue, syncope, influenza-like syndrome, paresthesia, headache, dizziness, neuropathy, seizures, cognitive impairment, low back pain, arthralgia, hemoptysis, gum bleeding, petechiae, cerebral infarction, peripheral edema, generalized edema, insomnia, pyuria, anemia, neutropenia, chest pain, herpes zoster, vision impairment, dry mouth, tinnitus, pneumonia, increased sputum, pharyngitis, upper respiratory tract infection, epistaxis, pleural effusion, constipation, abdominal pain, dyspepsia, oral ulceration, abdominal discomfort, dysphagia, heartburn, gastrointestinal disturbances, mucositis, epigastric discomfort, gastritis, respiratory failure, worsening of disease

Store this drug in a tightly sealed container to protect it from air or moisture, and keep it at room temperature between 1°C and 30°C. This storage method will help maintain the drug's effectiveness.

Appearance

Brown circular film-coated tablet

Package unit

10 tablets/PTPX3/box