Kwang Dong Sitagliptin Phosphate Hydrate Tablet 100 mg

Adult dose

This medication is administered once daily at a dose of 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. This medication can be taken regardless of meals. Dosage adjustments for patients with renal impairment: - Mild renal impairment (eGFR 60 or more but less than 90): No dosage adjustment needed - Moderate renal impairment (eGFR 45 or more but less than 60): No dosage adjustment needed - Moderate renal impairment (eGFR 30 or more but less than 45)

This medication may cause serious allergic reactions in some patients. These reactions may occur within three months of initial administration, so caution is required. There is a risk of acute pancreatitis, which is inflammation of the pancreas, during the use of this medication; therefore, if symptoms of pancreatitis such as abdominal pain, nausea, or vomiting occur, consult a physician immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in patients who have an allergy to this medication or its ingredients. Patients with decreased renal function should have their dosage adjusted; therefore, appropriate dosages should be determined through renal function tests. During the use of this medication, cold-like symptoms, headaches, gastrointestinal symptoms (abdominal pain, nausea, diarrhea) may occur, and some patients may experience hypoglycemia. Particularly when combined with insulin or sulfonylureas, there may be an increased risk of hypoglycemia, and dosage adjustment may be necessary. Rare adverse effects such as severe joint pain or skin blistering have been reported among patients taking this medication; if any of these symptoms appear, notify a doctor immediately and discontinue the medication. Use of this medication is not recommended for pregnant or breastfeeding women, and its safety and efficacy in children and adolescents under 18 years have not been confirmed. Elderly patients may experience decreased renal function, so renal function should be assessed before taking this medication, along with careful monitoring. In the case of overdose, general treatment should be administered, and blood dialysis may be considered as needed. This medication has relatively low drug interaction with other diabetes treatments, but caution is necessary when taken with specific medications.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe skin adverse reactions (Stevens-Johnson syndrome, rash, blisters, skin peeling, oral/ocular mucosal pain), acute pancreatitis (hemorrhagic or necrotizing pancreatitis), severe edema, urinary abnormalities, acute renal failure, liver abnormalities (elevated liver enzymes, jaundice), serious neurological symptoms (severe and disabling)

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• headache
• abdominal pain
• nausea
• diarrhea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a sealed container to prevent air from entering, and it is best kept at room temperature between 1°C and 30°C. Proper storage will maintain the medication's effectiveness and prevent degradation.

Appearance

Beige, round, biconvex film-coated tablet

Package unit

In-house packaging unit