Glivia Tablet 100 mg (Sitagliptin Phosphate Hydrate)

Adult dose

This medication is administered as 100 mg once daily, either alone or in combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. Renal impairment dosage adjustment: 1. Mild renal impairment (eGFR 60–90 mL/min/1.73 m2): No dosage adjustment needed 2. Moderate renal impairment (eGFR 45–60 mL/min/1.73 m2): No dosage adjustment needed 3. Moderate renal impairment (

This medication may rarely cause serious allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after taking it, you should stop taking it immediately and seek medical attention. Furthermore, this medication may cause inflammation of the pancreas, known as acute pancreatitis, during treatment. If symptoms such as abdominal pain, vomiting, or loss of appetite occur, you should visit a medical facility immediately. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and patients who have a hypersensitivity to this medication or its components should avoid taking it. Patients with impaired kidney function may need dose adjustments for this medication, so kidney function tests should be performed before use, and patients should follow their doctor's instructions. Side effects such as upper respiratory infections, nasopharyngitis, headaches, and diarrhea may occur during treatment, and if symptoms persist or worsen, consultation with a physician is recommended. When used in conjunction with insulin or sulfonylurea medications, there may be an increased risk of hypoglycemia, so blood sugar changes should be closely monitored, and dosage adjustments should be made when necessary. This medication is not recommended for women who are pregnant or breastfeeding, and its safety in children and adolescents under 18 years of age has not been established. In elderly patients, kidney function may decline, so it is advisable to regularly monitor kidney function before and during treatment. In case of overdose, general emergency measures should be implemented, and blood dialysis may be used to remove some of the medication, if necessary. This medication tends to have few interactions with other drugs, but it is safe to consult a doctor when taking certain medications. If sudden joint pain or skin blisters occur during treatment, stop taking it immediately and consult a specialist.

Serious side effects

• Hives, severe swelling (angioedema), chest tightness, shortness of breath, cold sweat, pallor → severe allergic reaction
• Severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain → severe skin adverse reaction
• Acute pancreatitis (including fatal/non-fatal hemorrhagic or necrotizing pancreatitis)
• Difficulty in breathing or shortness of breath, asthma attacks, abnormal respiratory symptoms accompanied by cough and fever
• Jaundice (yellowing of the skin or eyes)

Mild side effects

• Nasopharyngitis
• upper respiratory infections
• headaches
• diarrhea
• nausea
• constipation
• muscle pain
• limb pain
• back pain
• itching

This medication should be stored in a tightly closed container to prevent air or moisture from entering, ideally at a temperature between 1 and 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be maintained for a longer period.

Appearance

Beige, round, biconvex film-coated tablet

Package unit

28 tablets (14 tablets/PTP * 2)