Celec Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be taken with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg per dose twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks on 400 mg daily, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), reduce the dose to approximately 50% of the recommended daily dose.

This medication may cause a risk of gastrointestinal bleeding for individuals who drink alcohol regularly, so they must consult a doctor or pharmacist. For individuals with heart or vascular issues or risk factors, taking this medication may increase the risk of cardiovascular problems such as myocardial infarction or stroke; hence it should be used at the lowest dose for the shortest duration, with close observation of symptoms. This medication can cause serious gastrointestinal issues such as ulcers, bleeding, or perforation, so those with a history of gastrointestinal diseases or the elderly should be especially cautious. If symptoms like abdominal pain, indigestion, black stool, or vomiting of blood occur, seek medical attention immediately. Individuals allergic to this medication or sensitive to specific components, those with severe liver or kidney issues, active gastric ulcers or inflammatory bowel disease, as well as pregnant or breastfeeding women, should not take this medication. Those with impaired liver or kidney function, asthma, heart failure, hypertension, or edema should be more cautious when using this medication and should have regular tests to monitor liver and kidney function during treatment. This medication can interact with various drugs, so if taking other medications, it is essential to inform a doctor or pharmacist, particularly when combined with antihypertensives, diuretics, anticoagulants, or antidepressants. Pregnant women or those planning to become pregnant should not take this medication as it may harm the fetus, and breastfeeding women should consult before taking as it may affect the infant through breast milk. Safety and efficacy in pediatric and adolescent populations have not been established; therefore, use in those under 18 years of age is not advised. Older adults may have decreased kidney and liver function, so they should use this medication with particular caution, and dosage adjustment may be needed. If taking this medication for an extended period, regular blood tests and liver and kidney function tests should be conducted to monitor for abnormalities, and any unusual symptoms should be reported to healthcare providers. Dizziness or drowsiness may occur during use; therefore, caution is advised while driving or operating machinery. In case of overdose, symptoms like nausea, vomiting, drowsiness, increased blood pressure, and kidney failure may occur, requiring immediate medical attention.

Gastrointestinal hemorrhage, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, muscle tension, sensory reduction, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, back pain, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, insomnia, loss of appetite, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucination, exacerbation of epilepsy, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbating bronchospasm, dyspnea, laryngitis, pneumonia, nosebleeds, voice disorders, vesicular dermatitis, dermatitis, nail disease, photosensitivity, pruritus, erythematous rash, maculopapular rash, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, drug rash, arrhythmia, ventricular hypertrophy, angina, unstable angina, coronary artery disorders, myocardial infarction, heart failure, palpitations, tachycardia, stroke, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombophlebitis, vasculitis, deep vein thrombosis, intracerebral hemorrhage, monoclonal gammopathy, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, earache, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, elevated sodium levels, elevated potassium levels, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical strain, synovitis, tendinitis, myositis, fracture, tendon rupture, back pain, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic granuloma, contact dermatitis, injection site reactions, skin nodules, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, anaphylactic reaction, hallucinations, intracerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal hemorrhage, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular psoriasis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microfocal glomerulonephritis, female infertility

This medication should be stored in a tightly sealed container to protect it from air and moisture and kept at room temperature between 15 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and allow for safe use.

Appearance

White capsule filled with a powder that is white to light yellow with yellow stripes on both sides.

Package unit

30 capsules/bottle, 100 capsules/bottle