HanIn Sitagliptin Tablets 100 mg (Sitagliptin Phosphate Hydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. This medication can be taken regardless of meals. For patients with renal impairment, dose adjustment is necessary based on the glomerular filtration rate. - Mild and some moderate renal impairment patients do not require dose adjustment. - Patients with a glomerular filtration rate of 30-45 mL/min/1.73 m2 should take 50 mg once daily.

This medication may cause severe allergic reactions, so if symptoms such as rash or difficulty breathing occur, discontinue use immediately and consult a doctor. While taking this medication, inflammation of the pancreas, known as pancreatitis, may occur, so if symptoms like abdominal pain, vomiting, or loss of appetite arise, notify medical personnel promptly. It is advisable not to use this medication in patients with type 1 diabetes or diabetic ketoacidosis. Those who have experienced severe allergic reactions to this medication or its components should avoid taking it. Patients with impaired kidney function should adjust the dose of this medication, so regular kidney function tests before and during treatment are important. In clinical trials, patients taking this medication may experience side effects such as cold symptoms, headaches, and upper respiratory infections. Additionally, hypoglycemic symptoms may occur, so it is crucial to monitor blood sugar levels frequently and pay attention to symptoms, especially when taken with insulin or other sulfonylureas. If severe joint pain or blistering symptoms occur while taking this medication, discontinue use immediately and consult medical personnel. It is not safe for pregnant or nursing women to take this medication, and its safety and efficacy in children or adolescents under 18 years of age have not been established. Elderly patients may experience decreased kidney function, so dose adjustments and kidney function tests are necessary. In the case of overdose, it may be necessary to remove the drug from the gastrointestinal tract and monitor the condition with tests such as an electrocardiogram, and, if required, the drug can be removed through dialysis. Although no significant drug interactions have been reported with this medication when taken with numerous other drugs, caution may be necessary when combined with specific medications, so it is essential to inform medical personnel of other medications being taken.

Serious side effects

Hives, severe swelling (edema), hypersensitivity reactions (including anaphylaxis and angioedema), severe skin reactions (including Stevens-Johnson syndrome and exfoliative skin diseases), pancreatitis, acute pancreatitis, acute renal failure, difficulty breathing, severe edema, severe joint pain accompanied by disabilities, bullous pemphigoid, jaundice, severe allergic reactions, thrombocytopenia, rhabdomyolysis, pneumonia, cardiac arrest

Mild side effects

• Rhinitis
• upper respiratory infection
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be kept in a tightly sealed container to prevent air and moisture from entering. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the effectiveness of the medication for a long time.

Appearance

Beige, round, and biconvex film-coated tablet

Package unit

30 tablets/bottle, 90 tablets/bottle