Coxgreen Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be taken with or without food. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg per dose twice daily. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg per dose twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks on 400 mg daily, another treatment option should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. For patients with moderate hepatic impairment (Child-Pugh Class II), reduce the dose to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic drinks a day; it is essential to consult a doctor or pharmacist. It may increase the risk of cardiovascular diseases, and serious thromboembolic issues such as heart attack or stroke may occur, so it should only be used at the lowest effective dose for the shortest duration possible. Serious issues such as ulcers, bleeding, or perforation in the gastrointestinal tract may occur, so caution is especially needed for individuals with a history of gastrointestinal diseases or the elderly. This drug should not be administered to individuals with specific allergies, severe liver, kidney, or heart impairment, pregnant or breastfeeding women, or those with certain genetic disorders. Patients with poor liver or kidney function or a history of asthma, hypertension, or heart failure should take this medication cautiously and require regular monitoring. If any unusual symptoms occur during treatment, such as gastrointestinal pain, indigestion, black stools, sudden chest pain, shortness of breath, severe headaches, skin rashes, etc., immediate consultation with medical personnel is necessary. This medication can interact with various drugs, so if other medications are being taken, be sure to inform healthcare providers, especially when taking blood pressure medications, anticoagulants, antidepressants, or antibiotics. Women who are pregnant or planning to become pregnant should not take this medication and breastfeeding individuals should decide on the use in consultation with a specialist. Dizziness or drowsiness may occur during treatment, so it is recommended to avoid driving or operating dangerous machinery. Regular check-ups for liver, kidney, and blood tests are necessary during long-term use to monitor for anomalies; if any are found, the medication should be stopped immediately.

Gastrointestinal bleeding, cardiovascular thrombotic response, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, disorientation, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechial hemorrhage, angioedema, alopecia, vesicular dermatosis, peripheral edema, facial edema, influenza-like illness, injury, taste disorder, albuminuria, cystitis, hematuria, dysuria, frequent urination, kidney stones, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine blood, positive urine protein, impaired renal function, acute kidney failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, elevated CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, elevated alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various areas, muscle rigidity, decreased hematocrit, increased hemoglobin, petechial hemorrhage, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic syndrome, contact dermatitis, injection site reaction, skin nodules, headache, leg cramps, sensory impairment, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicidal tendencies, loss of smell, loss of taste, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, angioedema, anorexia, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infection, herpes simplex, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, mastalgia, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, elevated ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, fixed drug eruption, acute kidney failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, female infertility, menstrual disorders

This medication should be stored in a tightly sealed container to prevent air exposure, and the temperature should be maintained in a cool place between 15 and 30 degrees Celsius to preserve efficacy and safety.

Appearance

A white capsule filled with white to light yellow powder with yellow lines on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle