Celebrex Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication can increase the risk of gastric bleeding if taken by people who consume alcohol daily. Always consult with a doctor or pharmacist. This medication can cause cardiovascular issues and increase the risk of myocardial infarction or stroke, so it should be taken at the lowest effective dose for the shortest duration necessary. This medication can cause ulcers or bleeding in the gastrointestinal tract, so extra caution is needed for individuals with a history of gastrointestinal disease or elderly patients. Patients with allergic reactions or specific diseases, pregnant or breastfeeding women, and patients with severely impaired heart or kidney function should not take this medication. Patients with weak liver or kidney function, asthma, or hypertension need to be monitored closely by a doctor when using this medication. If symptoms such as headache, dizziness, indigestion, skin rash, chest pain, etc. occur during use, it's important to consult with healthcare personnel immediately. This medication can interact with other drugs, so it is necessary to inform the doctor of any other medications being taken, particularly caution is needed when combined with antihypertensives, anticoagulants, or antidepressants. Women who are pregnant or planning to conceive should avoid taking this medication, and if pregnancy is confirmed while taking it, treatment should be discontinued immediately. Elderly patients require careful observation due to the possibility of decreased kidney and heart function while taking this medication. Long-term use of this medication requires regular blood tests and evaluations of liver and kidney function. Excessive doses may cause symptoms such as vomiting, drowsiness, and gastrointestinal bleeding, requiring immediate medical attention. Keep this medication out of the reach of children, and be careful not to transfer it to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste alteration, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infections, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal impairment, acute renal failure, interstitial nephritis, headache, leg cramps, tension increase, sensory decrease, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, generalized edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reactions, angioedema, insomnia, loss of appetite, increased appetite, depression, neurological hyperreactivity, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infections, herpes simplex, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, mastalgia, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear disturbances, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urine urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, osteoarthritis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon ruptures, back pain, muscle rigidity, decreased hematocrit, elevated hemoglobin, petechiae, nosebleeds, thrombocytopenia, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reactions, skin nodules, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal impairment, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, anaphylaxis, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, biliary stasis, biliary stasis hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microfocal glomerulonephritis, female infertility

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and kept in a cool place between 15 to 30 degrees Celsius. This storage condition helps maintain the effectiveness of the medication and prevents deterioration.

Appearance

A white opaque hard capsule containing a white to yellowish powder

Package unit

30 capsules/bottle, 100 capsules/bottle