Avis Tablet

Adult dose

Usually, without regard to meals, 2 tablets are taken orally twice a day, morning and before bed. 1) Gastric and duodenal ulcers: Take 2 tablets twice a day or take 4 tablets once daily at bedtime. Particularly for duodenal ulcer patients, taking 4 tablets twice a day in the morning and at bedtime can achieve a higher treatment rate. The same dosage applies to ulcers due to NSAID use or in co-therapy to prevent the occurrence of gastric and duodenal ulcers in long-term NSAID use. Usually, conditions caused by NSAID use typically heal within 8 weeks, although in some patients, healing may take longer. For recurrent ulcer patients who have shown excellent short-term responses to this medication, a maintenance therapy of taking 2 tablets once daily at bedtime is recommended. 2) Gastroesophageal reflux disease: For 8 weeks, take 2 tablets twice a day or take 4 tablets once a day at bedtime. For severe reflux patients, the dosage may be increased to 4 tablets four times a day. 3) Zollinger-Ellison syndrome: Start with a dosage of 2 tablets three times a day, and it may be increased as needed. In severe cases, according to a doctor's directive, the total daily dose may reach up to 6 g of ranitidine. 4) Peptic ulcer, upper gastrointestinal bleeding due to acute stress ulcers and acute mucosal lesions: When oral administration becomes possible, switch from injection to oral administration and take 2 tablets twice a day. 5) Pre-operative dosing (Mendelson's syndrome prevention): Take 2 tablets 2 hours before induction of anesthesia. It is also beneficial to take 2 tablets the night before surgery.

This medication should not be used in patients with impaired kidney function or those undergoing dialysis. Furthermore, patients with a history of allergic reactions to this drug or any of its components should avoid its use. Patients with a rare disease known as acute porphyria may experience worsening symptoms and should not use this drug. In addition, patients who have undergone upper gastrointestinal tract surgery, pregnant women or those who may become pregnant, premature infants, and newborns, as well as patients who need to limit their potassium intake, should also avoid using this drug. Patients with compromised liver function, those with a history of drug allergies, elderly patients, and individuals with a history of kidney dysfunction should use this medication with caution. When taken with NSAIDs, special precautions are needed, and regular testing may be required. This medication can mask symptoms of gastric cancer, so it should only be administered to patients with gastric ulcers or those showing recent indigestion symptoms after ensuring that they do not have malignant diseases. Patients with Helicobacter pylori infection and gastric/duodenal ulcers may require bacterial eradication therapy. Caution should be exercised when used in critically ill patients in the intensive care unit, those with hypophosphatemia, and patients with swallowing difficulties. During use, rare allergic reactions, blood abnormalities, liver function abnormalities, cardiac arrhythmias, gastrointestinal symptoms, neuropsychiatric symptoms, muscle pain, and skin rashes may occur, so if any unusual symptoms arise, patients should consult a physician immediately. Long-term use is not recommended, and if there is no therapeutic effect, a change to another medication may be necessary. If dizziness or drowsiness occurs, patients should avoid driving or operating dangerous machinery. This medication may interact with other drugs, so it is important to inform healthcare providers of any other medications being taken, especially when taken in conjunction with anticoagulants, antibiotics, or analgesics. It is safest for pregnant or breastfeeding women to avoid this medication. Safety for pediatric use has not been established and it is not recommended for children. In case of overdose, emergency treatment such as vomiting or gastric lavage may be necessary, and blood dialysis may be helpful in some cases. Lastly, this medication may reduce stomach acid secretion, potentially promoting bacterial growth in the gastrointestinal tract, so ocular examinations may be required in long-term use.

Serious side effects

Shock (anaphylactic shock), hives, angioedema, bronchospasm, chest pain, vascular edema, reversible jaundice or non-jaundiced hepatitis, liver dysfunction, severe allergic reactions, severe swelling, acute interstitial nephritis, seizures, altered consciousness, myoclonus, bone marrow suppression, aplastic anemia, aplastic anemia, acquired immune hemolytic anemia, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), vasculitis,

Mild side effects

• Skin rash
• hives
• angioedema
• fever
• bronchospasm
• hypotension
• chest pain
• granulocytopenia
• reversible leukopenia
• thrombocytopenia

This medication should be stored in a tightly sealed container to protect it from exposure to air, and it is best to keep it at a temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness and prevent degradation.

Appearance

Green round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle