Nelson Celecoxib Capsule 200 Milligrams (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted according to the patient, and it may be administered regardless of meals. 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or in divided doses of 100 mg twice daily. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg per dose twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or in divided doses of 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment at 400 mg daily, another treatment method should be considered. 4. Acute pain and primary dysmenorrhea The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding for individuals who regularly consume more than three alcoholic beverages daily; therefore, it must be discussed with a doctor or pharmacist. It may increase the risk of cardiovascular disease, potentially leading to cardiac events such as myocardial infarction or stroke, and should only be used at the minimum effective dose for the shortest duration. Serious gastrointestinal issues such as perforation, ulcers, and bleeding may occur, particularly in older adults who are at greater risk. Those with allergies or specific medical conditions, such as severe liver or kidney dysfunction, active peptic ulcer disease, or heart failure, should not take this medication. Patients with compromised liver or kidney function, asthma, hypertension, or fluid retention and edema must use this medication with extra caution, following their doctor’s guidance. This medication can have various side effects, including dyspepsia, headache, dizziness, skin rash, hypertension, heart issues, and liver dysfunction. Consultation with healthcare personnel is crucial if any adverse effects occur. Regular monitoring of blood pressure, liver function, and kidney function is necessary during treatment, and extra caution is needed for elderly patients or those with cardiovascular risks. This medication has numerous interactions with other drugs; inform your doctor or pharmacist of all medications you are taking. Women who are pregnant, may become pregnant, or are breastfeeding should avoid this medication and should consult with their doctor before use if planning a pregnancy. It is advisable not to use this medication for children or adolescents as safety and efficacy have not been established. Dizziness or drowsiness may occur after administration, so it is safer to avoid driving or operating machinery.

Gastrointestinal bleeding, cardiovascular thromboembolic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, hemorrhage, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, distension, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, incontinence, urinary tract infection, blurry vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated blood sodium, elevated blood potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical strain, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various parts, muscle stiffness, reduced hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, folliculitis, contact dermatitis, injection site reaction, dermal nodules, headache, leg cramps, sensory decrease, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicidal ideation, anosmia, ageusia, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, vasculitis, angioedema, hallucinations, epilepsy exacerbation, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, mastalgia, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorder, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, increased ALT, increased AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, female infertility

This medication may be sensitive to air or moisture; therefore, it should be stored in a sealed container. The storage temperature should be maintained at room temperature between 15 and 30 degrees Celsius. This way, the effectiveness of the medication can be securely maintained for an extended period.

Appearance

An opaque hard capsule containing white to light yellow powder

Package unit

100 capsules/bottle, 30 capsules/bottle