Widers Cocks Capsule 200 Milligrams (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or 100 mg per dose in 2 divided doses daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib per dose 2 times daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or 100 mg per dose in 2 divided doses daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose 2 times daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic drinks per day; thus, it is essential to consult a doctor or pharmacist. This drug may cause serious cardiovascular issues such as thrombosis, myocardial infarction, or stroke, so it should be used in the smallest possible dose for the shortest duration; individuals without a history of cardiovascular disease should seek immediate medical attention if symptoms occur. Perforation, ulcers, or bleeding in the gastrointestinal tract may occur; particularly, elderly individuals or those with a history of gastrointestinal conditions should visit a medical facility immediately if symptoms such as epigastric pain, dyspepsia, black stools, or hematemesis arise. This medication should not be administered to individuals with a history of specific allergies, severe liver or kidney disorders, active gastric ulcers, heart failure, or those who are pregnant and should inform healthcare providers about such conditions. Patients with impaired liver or kidney function, hypertension, asthma, heart failure, or diabetes require careful evaluation and monitoring before taking this medication. Routine blood tests and monitoring of liver and kidney function should be done while taking this medication to detect any abnormalities early. If severe allergic reactions, skin rash, blisters, fever, itching, or other symptoms appear, discontinue the medication immediately and consult a healthcare provider. This medication may interact with other drugs, so inform healthcare providers of any current medications, especially when taking antihypertensives, diuretics, anticoagulants, antidepressants, or anticancer agents. Women who are pregnant or planning to become pregnant should avoid this medication as it may affect the fetus, and breastfeeding individuals should consult a healthcare provider before use. This medication's safety and efficacy have not been established for use in individuals under 18 years of age. Elderly individuals are at a greater risk for decreased kidney, liver, and heart function, so special attention and observation are required during administration. Dizziness or drowsiness may occur during treatment; therefore, driving or operating machinery is discouraged. In cases of overdose, symptoms may include nausea, vomiting, drowsiness, and gastrointestinal bleeding, so dosages must be adhered to, and medical attention should be sought if overdose is suspected. Store in a safe place out of reach of children, and do not transfer to another container.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechial bleeding, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, hypertonia, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormality, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, anorexia, increased appetite, depression, neuroirritability, somnolence, fatal intracranial hemorrhage, hallucination, epilepsy exacerbation, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchospasm, worsening bronchospasm, dyspnea, laryngitis, pneumonia, nosebleed, dysphonia, vesiculobullous dermatitis, dermatitis, nail disease, photosensitivity reaction, pruritus, erythematous rash, maculopapular rash, skin disease, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, drug rash, arrhythmia, left ventricular hypertrophy, angina pectoris, unstable angina, coronary artery disease, myocardial infarction, heart failure, palpitations, tachycardia, stroke, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombotic venous inflammation, vasculitis, deep vein thrombosis, cerebral hemorrhage, single organ failure, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, chest neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear anomalies, otalgia, presbycusis, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urine bilirubin, cholelithiasis, hepatitis, jaundice, hepatic failure, fulminant hepatitis, hepatic necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, anorexia, elevated LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, arthropathy, skeletal dysplasia, myalgia, cervical tension, synovitis, tendinitis, myositis, fracture, tendon rupture, back pain, muscle rigidity, decreased hematocrit, increased hemoglobin, nosebleed, thrombocytopathy, anemia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, pustulosis, contact dermatitis, injection site reaction, skin nodules, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute kidney failure, interstitial nephritis, menstrual disorders, chest pain, weakness, nausea, vomiting, upper abdominal pain, lethargy, drowsiness, upper gastrointestinal bleeding, acute kidney failure, respiratory depression, coma

This medication should be stored in a tightly sealed container to prevent air or moisture ingress, ideally at room temperature between 15 and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and prevent degradation.

Appearance

White to light yellow powder filled in a white capsule with yellow stripes on the top and bottom

Package unit

30 capsules/bottle, 100 capsules/bottle