Opti-Forin Eye Drops 0.05% (Cyclosporine) (Single Use)

Adult eye dose

Instill 1 drop in each eye twice daily, approximately 12 hours apart. Before use, turn the bottle upside down and mix to obtain a uniform white, opaque emulsion. If this medicine is used at the same time as artificial tears, it may be administered with a 15-minute interval. Discard any remaining solution and the container after administration.

This medication has not been studied in patients with a history of herpetic keratitis, so it should be used with caution. The effect of increased tear production has not been observed in patients using topical anti-inflammatory agents or punctal plugs. It should not be administered to patients with active eye infections or those who have or may have allergies to any component of this medication. The most common side effect when using this medication is a stinging or burning sensation in the eyes. Additionally, conjunctival hyperemia, eye discharge, tearing, eye pain, foreign body sensation, itching, ache, and visual disturbances have been reported rarely. Serious allergic reactions such as severe angioedema, swelling of the face or tongue, pharyngeal edema, and shortness of breath may also occur rarely, so caution should be exercised. According to domestic studies, about 7.8% of patients reported adverse reactions, most of which were mild symptoms such as burning sensation, dry eyes, pain, and congestion. This medication should only be used for ophthalmic purposes, and care should be taken to avoid direct contact of the container tip with the eye. Vision may temporarily be blurred after instillation, so it is advisable to avoid driving or operating hazardous machinery until vision clears. The safety of this medication has not been established during pregnancy, so it should be used cautiously under a doctor's judgment only when necessary. There is also insufficient research on whether this medication is excreted in breast milk; therefore, caution is advised during breastfeeding. The safety and efficacy of this product in children under 16 years of age have not been confirmed, so it is best not to use it in this age group. Opened containers should be discarded immediately after a single use, and care should be taken to avoid contaminating the tip by letting it come into contact with the eye or other surfaces. This medication should not be used while wearing contact lenses, and lenses can be reinserted after 15 minutes from removal before administration. Keep the medication out of reach of children, and be sure to dispose of any expired medication. Carcinogenicity studies have been conducted on the components of this medication; however, it is deemed safe at normal usage levels. Specific problems were not found in mutagenic or genotoxic tests, but some tests did show sister chromatid exchange induction reactions. In reproductive toxicity studies, side effects were observed only at high doses, while no issues such as infertility have been reported at normal doses.

• Burning sensation in the eyes
• conjunctival injection
• discharge
• epiphora
• eye pain
• foreign body sensation
• itching
• pain
• visual disturbances
• eye swelling

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is between 15 and 25 degrees Celsius to maintain the efficacy of the medication.

Appearance

A homogeneous solution that is white and opaque or slightly translucent in a white semi-transparent plastic container.

Package unit

0.4mL/tube × 30/box