Neo World Tablet 20 mg (Rabeprazole Sodium)

Adult dose

Gastric ulcers, duodenal ulcers: Take 10 mg orally once daily, and may take up to 20 mg once daily depending on symptoms. Erosive or ulcerative gastroesophageal reflux disease: Take 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms persist after 8 weeks of proton pump inhibitor (PPI) treatment, an additional 8 weeks of 10 mg or 20 mg orally twice a day may be administered. Gastroesophageal reflux disease symptoms relief: Take 10 mg once daily. If symptoms are not controlled after 4 weeks, further evaluation is required. After symptom resolution, on-demand therapy of 10 mg once daily may be used to control subsequent symptoms. Long-term maintenance therapy for gastroesophageal reflux disease: Depending on the patient, take 10 mg or 20 mg orally once daily. Helicobacter pylori eradication: Patients infected with Helicobacter pylori should undergo eradication therapy. A combination of this drug at 20 mg, clarithromycin 500 mg, and amoxicillin 1 g is recommended to be taken twice daily for 7 days. Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily. The dosage can be adjusted up to 120 mg once daily based on individual patient needs. Doses up to 100 mg may be given once daily, and 120 mg should be divided and given 60 mg twice daily. Patients with Zollinger-Ellison syndrome have been treated with this medication for up to 1 year. ◯ Liver disease patients: Adverse reactions have been reported in patients with liver cirrhosis undergoing hepatic encephalopathy; thus, it should be administered cautiously. ◯ Pediatric patients: Safety has not been established in children. ◯ Elderly patients: Caution is needed since they often have reduced liver function.

This medication should not be administered to certain patients. For example, it should be avoided in individuals allergic to this drug or its components or with a history of hypersensitivity reactions. Moreover, it is also safer for patients currently taking certain antibiotics or other medications, as well as women who are pregnant or breastfeeding, to avoid using this drug. Patients with poor liver function or the elderly require special caution when using this medication, and it should be administered carefully in those with a history of allergies. This drug can cause various side effects, and hypersensitivity reactions such as skin rash or itching may occur; therefore, it should be discontinued immediately if such symptoms arise. Regular laboratory tests are necessary as blood tests may reveal changes in red blood cells or white blood cells, liver function abnormalities, cardiac issues, digestive symptoms, and other adverse reactions. Psychological symptoms such as headache, insomnia, anxiety, and dizziness may occur, and in rare cases, depression or confusion may appear. Respiratory symptoms, muscle pain, skin issues, vision problems, and urinary issues have been reported in various bodily areas, so contact healthcare professionals if symptoms occur. Prolonged use of this drug may increase the risk of bone fractures; therefore, caution is needed for long-term use. Additionally, this drug may interact with other medications, necessitating dosage adjustments or changes in administration methods depending on the other medications taken. Women who are pregnant or breastfeeding should avoid using this medication, and the elderly have a higher risk of side effects due to reduced liver function. The safety of this medication in children has not been established, so it is advisable to refrain from use. In the event of an overdose, there is no specific antidote, so it is crucial to receive appropriate treatment and supportive care as per symptoms. This medication should be swallowed whole in tablet form without chewing or breaking, and it should be kept out of the reach of children. Lastly, any unusual symptoms that arise during the use of this medication should be reported to healthcare professionals for proper evaluation and treatment.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, fulminant hepatitis, liver dysfunction, jaundice, acute interstitial nephritis, hepatic encephalopathy, severe allergic reactions, serious neurological symptoms (convulsions, confusion, delirium, disorientation, seizures), respiratory issues (dyspnea, asthma, apnea, respiratory depression), skin abnormal reactions (toxic epidermal necrolysis (Lyell's syndrome), Stevens-Johnson syndrome, erythema multiforme

Mild side effects

• Rash
• urticaria
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia

This medication must be stored in a tightly closed container to avoid exposure to air or moisture and kept at room temperature between 1 and 30 degrees Celsius. This helps maintain the drug's effectiveness and prevent deterioration.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets/box [(14 tablets/Alu-Alu × 2)]