Celebrex 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient and may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200mg of celecoxib once daily, or 100mg twice daily. 2. Rheumatoid arthritis Take 100mg or 200mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) Administer 200mg of celecoxib once daily, or 100mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400mg daily. If no effect is observed after 6 weeks of treatment with 400mg daily, another treatment approach should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400mg of celecoxib, with an additional 200mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be used with caution in individuals who consume large amounts of alcohol daily, as it may increase the risk of gastrointestinal bleeding; consultation with a doctor or pharmacist is essential. It may increase the risk of cardiovascular disease, so it should be used at the lowest effective dose for the shortest duration. If cardiovascular symptoms occur, report them immediately. Serious gastrointestinal issues such as perforation, ulcers, and bleeding may occur, so those with a history of gastrointestinal diseases or older patients should take special care. This medication should not be used by individuals allergic to it, or by patients with severe liver, kidney, or heart conditions, pregnant or breastfeeding women. Patients with impaired liver or kidney function, hypertension, heart failure, or asthma should exercise caution when taking this medication and undergo regular monitoring. While taking this medication, various side effects such as indigestion, headache, dizziness, hypertension, edema, skin rash, etc., may occur; inform healthcare providers of any abnormal symptoms immediately. This medication is metabolized in the liver, so interactions may occur when taken with certain medications, especially blood pressure medications, anticoagulants, and antidepressants. Caution is needed when used in combination. Pregnant women or those planning to become pregnant should not take this medication, and if pregnancy is confirmed while taking it, discontinuation should occur immediately. Older patients are more likely to have reduced kidney and liver function, so care should be taken when using this medication, and dose adjustments may be necessary. For long-term use of this medication, regular blood tests and liver and kidney function assessments should be performed, and if abnormalities are found, discontinuation is advised. In the case of an overdose, symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding may occur, and immediate medical attention should be sought.

Gastrointestinal hemorrhage, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, hemorrhage, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confused states, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcers, esophageal ulcers, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, pollakiuria, kidney stones, incontinence, urinary tract infections, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, leg cramps, tension increase, sensory decrease, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, back pain, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, angioedema, insomnia, decreased appetite, increased appetite, depression, neuroexcitable reaction, drowsiness, fatal intracranial hemorrhage, hallucinations, worsening epilepsy, upper respiratory tract infections, sinusitis, pharyngitis, rhinitis, bronchitis, bronchial spasms, exacerbated bronchial spasms, dyspnea, laryngitis, pneumonia, epistaxis, voice disorders, vesicular dermatitis, dermatitis, nail diseases, photosensitivity reactions, pruritus, erythema rash, maculopapular rash, skin diseases, skin dryness, increased sweating, erythema multiforme, exfoliative dermatitis, mucocutaneous syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash with eosinophilia and systemic symptoms, arrhythmia, ventricular hypertrophy, angina, unstable angina, coronary artery disorders, myocardial infarction, heart failure, palpitations, tachycardia, stroke, aortic valve insufficiency, hematoma, sinus bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accidents, peripheral necrosis, thrombophlebitis, vasculitis, deep vein thrombosis, intracerebral hemorrhage, abscess, wound infections, gingivitis, herpes simplex, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, candidiasis, genital candidiasis, otitis media, mammary tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, elevated ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased sodium levels, increased potassium levels, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, decreased appetite, elevated LDH, hypoglycemia, hyponatremia, synovial sacs, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, fractures, tendon ruptures, back pain, muscle stiffness, reduced hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenic disorders, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, pleuritis, contact dermatitis, injection site reactions, skin nodules, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reactions, hallucinations, intracerebral hemorrhage, aseptic meningitis, taste loss, smell loss, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microangiopathic glomerulonephritis, menstrual disorders, female infertility, chest pain

Store this medication in a tightly sealed container to prevent exposure to air and moisture. The ideal storage temperature is between 1 and 30 degrees Celsius.

Appearance

White, oblong film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle