Celebrix Capsule 200mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient and may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, another treatment approach should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug may pose a risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic drinks per day, so it is essential to consult a doctor or pharmacist. This drug can increase the risk of serious cardiovascular side effects such as thrombotic events, myocardial infarction, and stroke, so the lowest possible dose should be used for the shortest duration, and cardiovascular symptoms should be monitored carefully. Serious problems such as perforation, ulcer, and bleeding in the gastrointestinal tract may occur, so special caution is needed for individuals with gastrointestinal issues or the elderly, and immediate medical attention should be sought if gastrointestinal bleeding or ulcer symptoms occur. This drug should not be administered to patients with specific allergies or conditions, such as sulfonamide allergy, severe liver or kidney disease, active peptic ulcer, heart failure, or women who are pregnant. For patients with compromised liver or kidney function or a history of asthma, hypertension, heart failure, or diabetes, careful administration is necessary, and their condition should be closely monitored during use. Various adverse reactions may occur during administration, including indigestion, headache, dizziness, skin rash, edema, hypertension, gastrointestinal bleeding, etc., so immediate consultation with a doctor is necessary if symptoms arise. Since this drug is metabolized in the liver, blood concentration may change when taken with certain medications, so dose adjustments and monitoring of condition are necessary during concurrent administration. Women who are pregnant or may become pregnant, and nursing mothers should not take this medication, and those planning to become pregnant should consult a doctor before use. The safety and efficacy of this medication have not been established for children and adolescents under 18 years of age, thus its use is not recommended. Elderly patients may have decreased kidney or liver function, so special caution is necessary during administration, and dose adjustments may be required. For long-term use of this drug, regular blood tests and liver and kidney function tests should be conducted to check for abnormalities, and if abnormalities are found, discontinuation may be necessary. In the case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and gastrointestinal bleeding may occur, and immediate medical attention should be sought for proper treatment. This medicine should be kept out of reach of children and should not be transferred to another container.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, headache, dizziness, constipation, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive rheumatoid factor, shingles, pneumonia, dyspnea, elevated ALT, hearing loss, anaphylactic reaction, hallucinations, intracerebral hemorrhage, aseptic meningitis, taste loss, smell loss, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized pustular psoriasis, exfoliative dermatitis, generalized bullous fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, and minimal change disease.

This medicine should be stored in a tightly sealed container to prevent air or moisture from entering. It is recommended to maintain the storage temperature between 15 and 30 degrees Celsius at room temperature to prolong the effectiveness of the drug.

Appearance

White to light yellow powder filled in a white hard capsule with yellow stripe on top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle