Celebrex Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient. It may be administered without regard to meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg per dose twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment at 400 mg daily, consider another treatment. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug should be consulted with a doctor or pharmacist if taken by individuals who consume large amounts of alcohol daily, as it may result in gastrointestinal bleeding. Individuals with heart or vascular issues or risk factors should use this medication for the lowest effective dose and the shortest duration possible, as it may increase the risk of cardiovascular diseases such as myocardial infarction or stroke. Patients with a history of gastric ulcers or bleeding should be carefully monitored when taking this medication, as it may increase the risk of gastrointestinal perforation, ulceration, and bleeding. This medication is not to be administered to individuals with certain allergies, severe liver or kidney disease, heart failure, inflammatory bowel disease, women who are pregnant or breastfeeding, and patients following certain surgeries. Patients with impaired liver or kidney function, asthma, hypertension, heart failure, edema, dehydration, elderly patients, and those with blood coagulation disorders should use this drug cautiously and may require regular check-ups if necessary. This medication can cause various adverse reactions, including dyspepsia, headache, dizziness, skin rash, hypertension, edema, and liver function abnormalities; if symptoms occur, patients should inform medical personnel immediately. During treatment, regular clinical examinations such as blood pressure, liver and kidney function tests should be performed, and if any signs of abnormalities are detected, discontinuation of the medication should be considered. This drug may interact with other medications, so it is important to inform healthcare providers about any other medications being taken, particularly if taking antihypertensives, diuretics, anticoagulants, antidepressants, or antibiotics. Women who are pregnant or planning to become pregnant should avoid this medication, and those who are breastfeeding should either avoid it or discontinue breastfeeding. Elderly patients should be especially careful with this medication, as they may have reduced liver and kidney function, and dosage adjustment may be necessary. Dizziness or drowsiness may occur after taking this medication; therefore, driving or operating machinery should be avoided. Prolonged use of this medication may affect reproductive ability, so women planning for pregnancy or undergoing infertility testing should consult a healthcare professional before taking it.

Gastrointestinal bleeding, cardiovascular thrombosis, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmias, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, increased liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, urinary frequency, nephrolithiasis, incontinence, urinary tract infection, visual disturbances, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine occult blood, positive urine protein, renal impairment, acute renal failure, interstitial nephritis, headache, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, back pain, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, chest pain, vesicular dermatitis, nail diseases, photosensitivity reactions, dermatitis, dry skin, increased sweating, erythema multiforme, lipoma, allergic dermatitis, petechiae, dandruff, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, contact dermatitis, injection site reaction, skin nodules, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various body parts, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, injury, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, pneumonia, epistaxis, dysphonia, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized bullous fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, nausea, constipation, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, chest pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive RA factor, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing impairment

This drug should be stored in a tightly closed container to prevent air from entering and should be kept at room temperature between 15 to 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness for a long time.

Appearance

A hard capsule filled with white to light yellow powder, with a white upper and lower part.

Package unit

30 capsules/bottle, 100 capsules/bottle