Celtive Capsule 200 milligrams (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted according to the patient and may be administered without regard to meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose as needed is 200 mg twice daily. ○ Patients with hepatic impairment In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medicine should be discussed with a doctor or pharmacist before taking, as it may cause gastric bleeding in those who consume more than three drinks a day regularly. This medication can increase the risk of cardiovascular thrombotic events, i.e., myocardial infarction or stroke, so it should be used at the lowest effective dose for the shortest duration necessary. If any cardiovascular symptoms such as chest pain, shortness of breath, weakness, or speech difficulties occur during use, you should immediately inform your healthcare provider. This medication increases the risk of gastrointestinal perforation, ulceration, bleeding, particularly for the elderly or those with a history of gastrointestinal diseases. If gastrointestinal symptoms such as epigastric pain, dyspepsia, black stools, or hematemesis occur, you should seek medical attention immediately. This medication is not to be administered to patients with certain allergies, severe liver or kidney diseases, active gastrointestinal bleeding, heart failure, or women who are pregnant or breastfeeding. Patients with impaired liver or kidney function, asthma, hypertension, or a history of cardiovascular diseases should use this medication with caution. Adverse reactions such as headaches, dizziness, dyspepsia, vomiting, skin rash, edema, hypertension, coughing may occur, and if symptoms are severe, consult a physician. This medication is metabolized in the liver, which may affect liver function and interact with other medications, so it is advisable to consult a healthcare professional before taking it with other drugs. Especially caution is needed when used in combination with antihypertensive agents, diuretics, anticoagulants, antidepressants, as it may increase the risk of renal impairment or bleeding. Women who are pregnant or planning to become pregnant should avoid taking this medication, and if pregnancy is confirmed while taking it, it should be discontinued immediately. Breastfeeding women should refrain from taking this medication as it may be excreted in breast milk, or they should discontinue breastfeeding. Safety in children and adolescents has not been established; therefore it should not be administered to those under 18 years of age. Elderly patients should be closely monitored for possible reductions in kidney, liver, and heart function when taking this medication. Regular blood tests and liver and kidney function tests should be performed when using this medication long-term, and it should be discontinued if any abnormalities are found. Dizziness or drowsiness may occur after taking the drug, so it is advisable to avoid driving or operating machinery. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and upper abdominal pain may appear, and immediate medical help should be sought. This medication should be kept out of reach of children, and transferring it to other containers should be avoided to maintain quality and safety.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, distension, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, itching, rash, hives, petechiae, angioedema, alopecia, vesicular dermatosis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, tension headache, sensory impairment, migraine, neuralgia, neuropathy, abnormal sensation, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reactions, angioedema, loss of appetite, increased appetite, depression, neurogenic reactions, drowsiness, fatal intracranial hemorrhage, hallucinations, aggravated epilepsy, upper respiratory infections, bronchospasm, exacerbated bronchospasm, shortness of breath, laryngitis, pneumonia, nosebleeds, voice disorders, vesicular dermatitis, dermatitis, nail diseases, photosensitivity reactions, pruritus, erythematous rash, papular rash, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, skin mucosal syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash associated with eosinophilia and systemic symptoms, arrhythmia, ventricular hypertrophy, angina pectoris, unstable angina, coronary artery disease, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, sinus bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accidents, peripheral gangrene, thrombophlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, solitary, wound infections, gingivitis, herpes simplex, shingles, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast pain, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, abnormal liver function, increased ALT, increased AST, elevated γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, elevated serum sodium, elevated serum potassium, increased BUN, elevated CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, elevated alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon ruptures, back pain, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eczema, contact dermatitis, injection site reactions, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, blurry vision, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal impairment, acute renal failure, interstitial nephritis, menstrual disorders, anaphylactic reactions, hallucinations, cerebral hemorrhage, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular rash, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, mild lesion glomerulonephritis, female infertility

This medication should be stored in a tightly sealed container to avoid exposure to air and moisture, in a cool place between 15 to 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication over time.

Appearance

A capsule filled with a white to pale yellow powder with upper and lower parts white.

Package unit

30 capsules/bottle, 100 capsules/bottle