Uriphen Tablets 10mg (Solifenacin Succinate)

Adult dose

The usual recommended dose for adults (including older adults) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This drug may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required in the following patients. 1. Patients with renal impairment No dosage adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance>30ml/min). In patients with severe renal impairment (creatinine clearance≤30ml/min), administer with caution and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dosage adjustment is necessary in patients with mild hepatic impairment. In patients with moderate hepatic impairment (Child-Pugh Class B), administer with caution and do not exceed 5mg once daily. 3. Patients receiving potent cytochrome P450 3A4(CYP3A4) inhibitors In patients receiving ketoconazole or another potent CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in patients with symptoms of poor urine output, significant gastrointestinal problems, severe muscle weakness, or glaucoma with high ocular pressure. Patients allergic to this drug or its ingredients should also avoid it. Patients undergoing hemodialysis or those with very poor liver and kidney function, as well as patients with certain genetic issues, should not use this medication for safety reasons. Patients at risk for poor urine output or with gastrointestinal obstruction or decreased motility, and those with moderate liver or kidney dysfunction should use this medication with caution. Additionally, patients taking specific medications or those with autonomic nervous system issues should be cautious. Common side effects include dry mouth, constipation, dry eyes, and dizziness, and blurred vision may occur rarely, so caution is advised when driving or operating machinery. Severe side effects such as intestinal obstruction, angioedema, and allergic reactions have been reported, and any unusual symptoms should be consulted with a doctor immediately. This medication is metabolized by certain enzymes in the liver, so taking it with drugs that strongly inhibit these enzymes may increase the concentration of this medication and the risk of side effects. Therefore, dosage adjustments may be needed if such medications are being taken. It is best to avoid this medication during pregnancy or breastfeeding due to uncertainty about its safety. Safety and efficacy in children have not been established, so it should not be used in this population. In case of overdose, symptoms may include headache, dizziness, drowsiness, and blurred vision, and in severe cases, professional treatment may be required. Before taking this medication, patients must discuss existing health conditions or medications with a healthcare professional, and report any adverse reactions immediately.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colon obstruction
• intestinal obstruction
• angioedema
• nausea

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. Additionally, it should be kept at room temperature between 1 to 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance

Bright pink round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle