Coxivito Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient, and it may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or divide the dose into 100 mg per dose 2 times daily. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg per dose 2 times daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or divide the dose into 100 mg per dose 2 times daily. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose as needed is 200 mg per dose 2 times daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be consulted with a physician or pharmacist if you regularly consume three or more alcoholic beverages daily. Consuming this medication while frequently drinking alcohol may increase the risk of gastrointestinal bleeding. This medication can increase the risk of serious cardiovascular thrombotic events, such as myocardial infarction or stroke. Such risks may increase with higher doses and longer duration of treatment, therefore it is important to take the minimum effective dose for the shortest duration possible. This medication can cause serious problems such as gastrointestinal perforation, ulcers, and bleeding, and those particularly at risk include the elderly or those with a history of gastrointestinal disease. If symptoms such as epigastric pain, dyspepsia, black stools, or hematemesis occur, immediate medical attention is necessary. This medication should not be administered to individuals with specific allergies or medical conditions, and it should be avoided by women who are pregnant or breastfeeding. Individuals with impaired liver or kidney function, as well as those with heart disease, hypertension, or asthma, should use this medication cautiously and according to a physician's instructions. Regular monitoring of blood pressure, liver function, and kidney function may be required during treatment, and any abnormal symptoms should be reported immediately. This medication may interact with several other medications, so it is essential to inform your physician or pharmacist of any other medications you are taking. Pregnant women or those planning pregnancy should not take this medication, as it may affect the fetus, and caution is required while breastfeeding. This medication is not recommended for children or adolescents under 18 years of age as its safety and efficacy have not been established in this population. In the elderly, careful observation is necessary as kidney and liver function may be impaired. Dizziness or drowsiness may occur after taking this medication, so caution is advised when driving or operating machinery. During treatment, gastrointestinal discomfort, headache, dizziness, skin rash, edema, increased blood pressure, and other adverse reactions may occur, and if symptoms persist or worsen, immediate consultation with a physician is needed.

Gastrointestinal bleeding, cardiovascular thromboembolic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste alteration, albuminuria, cystitis, hematuria, dysuria, pollakiuria, kidney stones, incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, elevated alkaline phosphatase, weight gain, decreased appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fracture, tendon rupture, pain in the neck, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, angioedema, contact dermatitis, injection site reaction, skin nodules, headache, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, exacerbation of allergies, allergic reactions, asthenia, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, angioedema, decreased appetite, increased appetite, depression, neurosecretion response, drowsiness, fatal intracranial hemorrhage, hallucinations, seizure exacerbation, upper respiratory tract infection, herpes zoster, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, hepatic dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, hepatic failure, fulminant hepatitis, hepatic necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease glomerulonephritis, female infertility

This medication should be stored in a tightly sealed container that allows for proper ventilation, and it should be kept in a cool place between 15 to 30 degrees Celsius. Proper storage can help maintain the medication's effectiveness and prevent deterioration.

Appearance

A white hard capsule filled with white or pale yellow powder with blue horizontal stripes

Package unit

30 capsules/bottle, 100 capsules/bottle