Selbest Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be administered with or without food. 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg per dose twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist before use by individuals who consume a lot of alcohol daily; otherwise, there is a risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular thrombotic events, which can lead to severe situations such as myocardial infarction or stroke. Therefore, it should be taken at the minimum effective dose and for the shortest duration possible. Individuals with a history of gastrointestinal diseases should take special caution, as this medication can cause ulcers or bleeding in the stomach; if symptoms such as abdominal pain, dyspepsia, tarry stools, or hematemesis occur, medical personnel should be notified immediately. This medication should not be given to individuals with certain allergies or diseases, and patients with severely impaired liver or kidney function, or women who are pregnant or breastfeeding should avoid it. Patients with liver or kidney disease, asthma, heart failure, hypertension, or diabetes should use this medication with more caution, and should regularly check their condition according to their doctor’s instructions. While taking this medication, various side effects such as headaches, dizziness, dyspepsia, skin rash, edema, hypertension, and cough may occur, and if any abnormal symptoms appear, consult medical personnel. As this drug is metabolized in the liver, interactions with other medications may occur. Dose adjustments may be necessary when taken with medications that inhibit or induce liver enzymes, so inform your physician about any other medications you are taking. Women who are pregnant or planning to become pregnant should avoid this medication as it may affect reproductive capability. Additionally, breastfed infants may be exposed through breast milk, so caution is advised. Elderly patients usually have decreased kidney, liver, and heart function, thus should exercise more caution when taking this medication, starting at the minimum dose is recommended. Long-term use of this medication requires regular blood tests and liver and kidney function tests; if any abnormal findings are detected, discontinue use immediately. In the case of overdose, symptoms such as nausea, vomiting, drowsiness, and lethargy may arise and, in severe cases, renal failure or respiratory depression may occur, necessitating immediate medical attention. Store out of reach of children in a secure location and avoid transferring to another container.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tone increase, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, taste disorder, albuminuria, cystitis, hematuria, dysuria, frequent urination, nephrolithiasis, incontinence, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, chest pain, peptic ulcer, hemorrhagic colitis, esophageal perforation, intestinal obstruction, intestinal perforation, intestinal obstruction, alveolar osteitis after tooth extraction, enteric ulcer, melena, glossitis, aphthous stomatitis, oral mucosal vesicular formation, numbness of the mouth, oral pain, headache, leg cramps, hypertonicity, sensory reduction, migraine, neuralgia, neuropathy, dysesthesia, ataxia, suicide, loss of smell, loss of taste, weakness, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, insomnia, loss of appetite, increased appetite, depression, neurogenic reactions, drowsiness, fatal intracranial hemorrhage, confusion, hallucinations, seizure aggravation, upper respiratory infections, sinusitis, pharyngitis, rhinitis, bronchospasm, exacerbating bronchospasm, dyspnea, laryngitis, pneumonia, epistaxis, speech disturbance, vesicular dermatitis, dermatitis, nail disorders, photosensitivity reaction, pruritus, erythematous rash, maculopapular rash, skin disorders, dry skin, increased sweating, erythema multiforme, lipoma, allergic dermatitis, petechiae, dandruff, drug rash accompanied by eosinophilia and systemic symptoms, arrhythmia, left ventricular hypertrophy, exacerbating hypertension, angina, unstable angina, coronary artery disorders, myocardial infarction, heart failure, palpitations, tachycardia, stroke, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombotic venous inflammation, vasculitis, deep vein thrombosis, cerebral hemorrhage, multiple, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, menstrual cramps, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursa, arthralgia, arthrosis, skeletal abnormalities, myalgia, neck stiffness, synovitis, tendinitis, myositis, fracture, tendon rupture, back pain, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reaction, skin papules

This medication should be stored in a tightly closed container to avoid exposure to air and moisture. It is recommended to maintain a storage temperature between 15 to 30 degrees Celsius.

Appearance

White to off-white powder filled in a white hard capsule with yellow stripes on the top and bottom

Package unit

30 capsules/bottle, 500 capsules/bottle