Hancox Capsule 200mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks at 400 mg per day, another treatment should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a physician or pharmacist if taken by individuals who consume large amounts of alcohol daily, as there is a risk of gastrointestinal bleeding. Caution is advised as this medication may cause cardiovascular problems such as myocardial infarction or stroke in patients with heart or vascular issues or risk factors. This drug can cause gastric injury or bleeding, especially in the elderly or those with a history of gastrointestinal disease. Patients with allergies to this drug or certain liver, kidney, or heart diseases, as well as pregnant or breastfeeding women, should not take this medication. Use cautiously in individuals with impaired liver or kidney function, a history of asthma, hypertension, or heart failure. While taking this medication, various side effects such as headache, dizziness, indigestion, skin rash, swelling, hypertension, and difficulty breathing may occur; consult healthcare personnel if any abnormal symptoms arise. As this medication is metabolized in the liver, interactions may occur when taken with certain drugs. If you are taking other medications, be sure to inform your medical provider. Women who are pregnant or planning to become pregnant should not take this medication and should stop immediately if discovered to be pregnant. Elderly individuals may have decreased renal, liver, or heart function; extra caution is needed when taking this medication. Long-term use of this drug requires regular blood tests or liver and kidney function tests; if any abnormalities are found, stop taking the drug. In case of overdose, symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding may occur, and immediate medical attention is required.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory reduction, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, angioedema, loss of appetite, increased appetite, depression, neuro-excitability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infections, bronchospasm, exacerbation of bronchospasm, dyspnea, laryngitis, pneumonia, nosebleed, voice disorders, vesicular dermatitis, dermatitis, nail disorders, photosensitivity reactions, pruritus, erythematous rash, papular rash, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, arrhythmia, left ventricular hypertrophy, angina, unstable angina, coronary artery disorder, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombophlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, solitary, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic changes of the breast, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon rupture, back pain, muscle stiffness, reduced hematocrit, increased hemoglobin, nosebleed, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, paronychia, contact dermatitis, injection site reactions, skin nodules, taste disorder, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, incontinence, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reactions, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitive reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized pustular dermatitis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microangiopathic glomerulonephritis, female infertility.

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best kept at a temperature between 15 and 30 degrees Celsius. Proper storage ensures the medication maintains its effectiveness.

Appearance

White to light yellow powder filled in white hard capsules with yellow stripes on top and bottom

Package unit

30 capsules/bottle, 100 capsules/bottle