Celecixil Capsule (Celecoxib)

Adult dosage

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks at 400 mg per day, another treatment should be considered. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist if the patient consumes a lot of alcohol daily, as it may cause gastrointestinal bleeding. It can increase the risk of cardiovascular disease, so patients with a history of heart disease or stroke, or risk factors, should use the minimum dose for the shortest duration, and must inform medical personnel immediately if cardiovascular symptoms occur. Patients with a history of gastrointestinal ulcers or bleeding should take this medication with caution, and seek medical attention if symptoms like epigastric pain, indigestion, black stool, or vomiting blood occur. Patients who have an allergic reaction to this drug or have certain liver, kidney, or heart diseases, women who are pregnant or breastfeeding, or those with certain genetic diseases should not take this medication. Extra caution is required for those with liver or kidney issues, asthma, hypertension, heart failure, fluid retention, the elderly, and regular monitoring may be necessary. Dizziness or sleepiness may occur during treatment, so it is advisable to avoid driving or operating machinery. This drug can interact with other medications, so patients must inform their doctor or pharmacist about any other drugs they are taking, especially hypertension medications, anticoagulants, antidepressants, and antibiotics. Women who are pregnant or planning to become pregnant should consult with their doctor before taking this medication, as it may affect fertility. If discovered during pregnancy, use should be stopped immediately. Safety in children or adolescents has not been established, so it is not to be used in individuals under the age of 18. Overdose can lead to symptoms such as nausea, vomiting, and lethargy, requiring immediate medical assistance. This medication should be stored out of reach of children and should not be transferred to another container.

Gastrointestinal bleeding, cardiovascular thrombotic response, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine occult blood, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various areas, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, folliculitis, contact dermatitis, injection site reaction, skin nodules, chest pain, headache, dizziness, constipation, thirst, aphthous stomatitis, gastritis, allergy, low back pain, hyperlipidemia, hearing loss, anaphylaxis, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug exanthem with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, menstrual disorders, female infertility

This medication should be stored in a sealed container that prevents air from entering and should be maintained at a temperature between 15 and 30 degrees Celsius. Storing it this way will help maintain the medication's efficacy.

Appearance

A white hard capsule containing a white to light yellow powder.

Package unit

30 capsules/bottle, 100 capsules/bottle