CELECOXIB 200mg Tablets

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative joint disease): Take 200mg of celecoxib once daily, or divide the dose into 100mg twice daily. 2. Rheumatoid arthritis: Take 100mg or 200mg of celecoxib per dose, 2 times daily. 3. Ankylosing spondylitis (AS): Administer 200mg of celecoxib once daily, or divide the dose into 100mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400mg per day may be administered. If no effect is observed after 6 weeks of treatment with 400mg per day, another treatment method should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400mg of celecoxib, with an additional 200mg administered on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200mg per dose, 2 times daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Patients who drink alcohol regularly more than three times a day should consult a doctor or pharmacist before taking this medication. This medication may increase the risk of cardiovascular thrombotic events, myocardial infarction, or stroke, so it should be used at the lowest effective dose and for the shortest duration possible. Careful attention should be given to patients with gastrointestinal issues or elderly patients due to the risks of gastrointestinal bleeding, ulceration, or perforation. Patients with allergies to this medication or specific ailments, pregnant or breastfeeding women, and those with severe liver or kidney dysfunction should not take this medication. Patients with impaired liver or kidney function, asthma, heart failure, hypertension, and diabetes should use this medication with caution. During treatment, any unusual symptoms such as gastrointestinal pain, black stools, or hematemesis, cardiovascular symptoms, or skin rashes should be reported to a doctor immediately. This medication may interact with several other drugs, so patients taking other medications should inform their doctor, especially if taking antihypertensive agents, anticoagulants, or antidepressants. Women who are pregnant or planning to become pregnant should not take this medication, and it should be discontinued immediately upon confirmation of pregnancy during treatment. Elderly patients may have diminished renal and cardiac function, necessitating closer observation during treatment. Caution is advised as dizziness or drowsiness may occur, so driving or operating machinery is not recommended. Prolonged use of this medication requires regular blood tests and liver and kidney function tests. Overdose may result in symptoms such as nausea, vomiting, and drowsiness, requiring immediate medical attention. This medication should be stored out of reach of children and should not be transferred to another container.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, increased liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory depression, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, ageusia, back pain, allergy exacerbation, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, loss of appetite, increased appetite, depression, neuroexcitation, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infections, bronchospasm, exacerbation of bronchospasm, respiratory distress, laryngitis, pneumonia, nosebleed, speech disorders, vesicular dermatitis, dermatitis, nail diseases, photosensitivity reactions, pruritus, erythematous rash, papular rash, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, mucous membrane syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash, arrhythmia, left ventricular hypertrophy, angina, unstable angina, coronary artery disorder, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral necrosis, thrombophlebitis, vasculitis, deep vein thrombosis, intracerebral hemorrhage, herpes simplex, wound infection, gingivitis, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic change of the breast, thoracic neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, increased serum sodium, increased serum potassium, elevated BUN, elevated CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, elevated LDH, hypoglycemia, hyponatremia, synovial bag, arthralgia, arthropathy, skeletal dysplasia, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon rupture, back pain, muscle stiffness, decreased hematocrit, increased hemoglobin, nosebleed, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, folliculitis, contact dermatitis, injection site reactions, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, blurry vision, cataract, conjunctivitis, eye pain, glaucoma, eye hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal function impairment, acute renal failure, interstitial nephritis, menstrual disorders, female infertility, chest pain, anaphylactic reaction, hallucinations, intracerebral hemorrhage, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, bile stasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalised exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and it is best kept at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness.

Appearance

White oblong film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle