Lipien Tablet 20 mg (Atorvastatin Calcium Trihydrate)

Adult dose

The recommended initial dose for patients with hyperlipidemia is 10 mg once daily; if more LDL-cholesterol reduction is needed, it can be started at 20 mg or 40 mg once daily. The range of the dosing is 10 to 80 mg once daily. Lipid levels should be checked within 2 to 4 weeks after starting treatment to adjust the dosage. In patients with homozygous familial hypercholesterolemia, the dosing range is 10 to 80 mg once daily.

Child dose

The recommended initial dose for pediatric patients (10 to 17 years) with heterozygous familial hypercholesterolemia is 10 mg daily, with a maximum dose of 20 mg daily. The dosage should be adjusted at intervals of 4 weeks or more.

This medication must be stopped immediately if any unusual muscle symptoms occur. Muscle pain or weakness can progress to a serious condition called rhabdomyolysis, so caution is required. This medication can affect liver function, thus should not be used in patients with liver disease or impaired liver function. Additionally, pregnant women or those who may become pregnant, as well as breastfeeding women, should not take this medication. Children under the age of 10 should not use this medication, and careful use is required for children aged 10 to 17 years under the direction of a physician. This medication may interact with certain drugs taken together, so if taking other medications, it is essential to inform a healthcare provider or pharmacist. In particular, the risk of muscle abnormalities may increase when used with medications that inhibit enzymes that break down drugs in the liver. During use, if symptoms such as muscle pain, fatigue, malaise, or fever occur, it is crucial to inform a healthcare professional immediately and undergo tests. Regular liver function tests and blood tests to check for abnormalities are also important. This medication may increase drug concentration if taken with grapefruit juice; hence, it is advisable to avoid grapefruit juice intake. Elderly or patients with impaired kidney function are at a higher risk for muscle abnormalities, requiring closer monitoring and potential adjustments in medication dosage. Finally, this medication should be kept out of reach of children and stored securely in its original container with the seal intact.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, high fever with severe rashes, blisters, skin peeling, pain in oral/eye mucous membranes, severe skin abnormalities, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanying cough + fever, respiratory problems, skin or eyes turning yellow (jaundice), extreme malaise, liver abnormalities (jaundice), sudden

Mild side effects

• Weakness
• malaise
• chest pain
• peripheral edema
• fatigue
• fever
• pharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly sealed container to protect it from air and moisture. It should be stored at room temperature, ideally between 1 to 30 degrees Celsius, avoiding extremes of temperature.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle