Alpezil Tablet 5 mg (Donepezil Hydrochloride)

Adult dose

Adult: Donepezil hydrochloride should be administered as 5 mg once daily before bedtime. Donepezil reaches normal levels 15 days after administration, so for 4-6 weeks, 5 mg is to be administered. After evaluating the clinical response during this period, the dose may be increased up to 10 mg. When increasing to 10 mg daily, ensure attention is paid to gastrointestinal adverse reactions. Underweight women aged 85 and over should take no more than 5 mg daily.

Child dose

Pediatric: There is no experience with use in children.

This medication should not be used by women who are allergic to any of its components, pregnant or nursing, or by patients with certain genetic lactose metabolism disorders. Patients with heart disease or a history of peptic ulcers, those with asthma or lung diseases, patients with movement disorders such as Parkinson's disease, and those allergic to dyes included in this medication should use it with caution. Serious side effects such as slowed heart rate, arrhythmia, gastrointestinal bleeding, liver dysfunction, seizures, movement disorders, muscle issues, respiratory distress, acute pancreatitis, acute kidney failure, and sudden death may occur. Therefore, if any abnormal symptoms appear, consult a physician immediately. Additionally, various side effects such as nausea, vomiting, diarrhea, headache, fatigue, insomnia, dizziness, and skin rashes have been reported, so symptoms should be monitored closely. This medication is only to be used for the treatment of Alzheimer's disease and not for other types of dementia or memory disorders. Treatment should be carried out under the diagnosis and supervision of a specialist, and if no therapeutic effect is observed, discontinuation should be considered. Patients with heart disease should closely monitor heart rate and ECG changes while taking this medication, and those with a history of peptic ulcers should carefully monitor gastrointestinal symptoms. Dizziness or fatigue may occur when driving or operating machinery, so caution is required. Pregnant or nursing women are advised against using this medication, and if absolutely necessary, should consult with a specialist.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied by respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination issues

Mild side effects

Fatigue, pain, toothache, lethargy, weakness, swelling (including facial swelling), fever, decreased body temperature, diarrhea, nausea, vomiting, abdominal disturbances (including abdominal pain), constipation, fecal incontinence, salivation, swallowing difficulties, headache, dizziness, insomnia, tremors, drowsiness, anxiety, aggressive behavior, hallucinations, confusion, drowsiness, increased libido, talkativeness, mania, nightmares, irritability, nonsensical speech, delusions, depression, confusion, apathy, hyperactivity, sexual desire (libido)

This medication should be stored in a tightly sealed container to prevent air exposure, and it is best kept at a temperature between 1°C and 30°C. Proper storage helps maintain the medication's efficacy over time.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle