Celecoxib Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of treatment with 400 mg per day, consider another treatment approach. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause serious side effects, such as gastrointestinal bleeding, if taken by individuals who regularly consume alcohol in excess of the recommended amount, so one should consult a doctor or pharmacist. This medication may increase the risk of cardiovascular thrombotic events, and there is the possibility of severe cardiovascular problems such as myocardial infarction or stroke occurring. Therefore, it is important to use the minimum effective dose for the shortest duration possible, and seek medical attention immediately if cardiovascular symptoms appear. There is a risk of affecting the gastrointestinal tract, causing complications such as upper and lower gastrointestinal perforations, ulcers, and bleeding, particularly in elderly patients or those with a history of gastrointestinal disorders. If symptoms such as abdominal pain, indigestion, black stools, or hematemesis occur, medical personnel should be notified immediately. This medication should not be administered to patients with specific allergic histories, severe liver or kidney impairments, active peptic ulcers or inflammatory bowel diseases, heart failure, or to pregnant or nursing mothers. Patients with impaired liver or kidney function, asthma, hypertension, or edema should exercise special caution when taking this medication and may require regular monitoring. Dizziness or drowsiness may occur while taking this medication, so it is advisable to avoid driving or operating machinery. Additionally, there may be interactions with other medications, so if currently taking any other drugs, one should inform a doctor or pharmacist, and special caution is needed when used with blood pressure medications, diuretics, anticoagulants, and antidepressants. Women who are pregnant or may become pregnant should not take this medication, and if pregnancy is confirmed while taking it, it should be discontinued immediately. Long-term use of this medication may cause anemia, liver and kidney dysfunction, and skin adverse reactions, so regular blood tests and assessments of liver and kidney function are necessary. In case of overdose, symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding may manifest, and one should visit a medical institution for appropriate treatment immediately. Lastly, this medication should be kept out of the reach of children, and transferring it to another container may affect the quality.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcers, esophageal ulcers, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, hypertonia, sensory impairment, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reactions, angioedema, loss of appetite, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infections, sinusitis, pharyngitis, rhinitis, bronchial spasms, exacerbated bronchial spasms, dyspnea, laryngitis, pneumonia, nosebleeds, voice disorders, vesicular dermatitis, eczema, nail diseases, photosensitivity reactions, itching, erythematous rashes, macular and papular rashes, skin diseases, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash with eosinophilia and systemic symptoms, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease nephritis, menstrual disorders, chest pain, bursitis, contact dermatitis, injection site reactions, skin nodules, ageusia, albuminuria, cystitis, hematuria, dysuria, frequent urination, kidney stones, urinary incontinence, urinary tract infections, blurred vision, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine haematuria, positive urine protein, renal dysfunction, interstitial nephritis, synovial sac, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, headache, dizziness, constipation, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive RA factor, shingles, pneumonia, dyspnea, elevated ALT, hearing loss

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is advisable to maintain a storage temperature between 15 to 30 degrees Celsius at room temperature. Storing it this way will help maintain the effectiveness of the medication for a long time.

Appearance

A white capsule filled with powder that is white to light yellow with yellow stripes on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle