Barocox Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment at 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding in individuals who consume three or more alcoholic drinks regularly, so it is essential to consult a physician or pharmacist. This medication may increase the risk of serious cardiovascular side effects such as thrombotic events, myocardial infarction, and stroke, so it should be used at the lowest effective dose for the shortest duration possible. There is a risk of gastrointestinal perforation, ulcer, and bleeding, particularly in elderly patients or those with a history of gastrointestinal disorders, who should exercise more caution. If you experience symptoms such as epigastric pain, indigestion, black stools, or hematemesis while taking this medication, inform medical personnel immediately. Patients with hypersensitivity, certain allergy histories, severe liver or kidney impairments, active peptic ulcers, gastrointestinal bleeding, a history of heart failure or cardiovascular diseases, pregnant or breastfeeding women, and those with specific genetic disorders should not take this medication. Patients with liver or kidney impairment, asthma, hypertension, heart failure, edema, elderly individuals, and diabetic patients need to take special care and administer this medication cautiously according to a physician's instructions. During treatment, regular blood tests and liver and kidney function tests should be conducted, and any adverse reactions should be reported immediately. This medication can interact with various drugs, so patients taking other medications should inform their healthcare provider, particularly when combining it with antihypertensives, anticoagulants, antidepressants, antibiotics, diuretics, etc. Women who are pregnant or planning to become pregnant should not use this medication, and breastfeeding women should either avoid taking it or discontinue breastfeeding. Elderly patients are at increased risk for gastrointestinal bleeding and renal function deterioration with this medication, so they should adjust the dose and take it cautiously. Taking this medication may cause dizziness or drowsiness, so caution is advised when driving or operating machinery. In case of overdose, symptoms such as nausea, vomiting, lethargy, gastrointestinal bleeding, and renal failure may occur, and appropriate medical treatment should be sought immediately. This medication should be kept out of reach of children, and it is safer not to transfer it to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, urinary tract infections, blurred vision, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, leg cramps, hypertonia, sensory loss, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicidal thoughts, anosmia, ageusia, back pain, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden cardiac death, anaphylactoid reaction, angioedema, loss of appetite, increased appetite, depression, neuroexcitation, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, breast fibrocystic disease, thoracic neoplasia, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, ear pain, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon ruptures, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic pneumonia, contact dermatitis, injection site reactions, skin nodules, blurred vision, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, chest pain, anaphylactic reactions, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, phototoxic reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is important to store it at room temperature between 15 and 30 degrees Celsius to maintain its efficacy.

Appearance

White to pale yellow powder filled in a white hard capsule with yellow bands at the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle, 500 capsules/bottle