Medication info
Limapri Tablet (Limaprost Alfadex)

Limapri Tablet (Limaprost Alfadex)

Prescription medicationTabletOral
Ingredient · strength
Limaprost Alfadex›166.67μg / 1 tablet
Manufacturer / importer
Kips Biopharma Co., Ltd.
Appearance
White round tablet
Packaging
84 tablets (21 tablets/PTP X 4)
Approval status
Active

MFDS item code 201500392 · Approved 2015.01.26 · Insurance code 693201400

Summary

Main use
Improvement of symptoms and walking ability in acquired lumbar spinal stenosis, and improvement of ischemic symptoms in Buerger's disease
Who takes it
Adults
Adult dose
For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally, 3 times daily. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability due to acquired lumbar spinal stenosis (patients with normal SLR test results and bilateral intermittent claudication), the usual adult dose is 1 tablet orally, 3 times daily. The dose may be adjusted according to age and symptoms.

Ingredients

Manufacturer
Kips Biopharma Co., Ltd.

Efficacy & effects

Improvement of symptoms and walking ability in acquired lumbar spinal stenosis, and improvement of ischemic symptoms in Buerger's disease

  • Ulcers
  • pain
  • cold sensations
  • lower extremity pain
  • lower extremity numbness
View approved original text

This medication helps improve ischemic symptoms such as ulcers, pain, and cold sensations due to obstructive thromboangiitis. It also alleviates subjective symptoms such as lower extremity pain or numbness in patients with acquired lumbar spinal canal stenosis and is effective in improving walking ability. It is used to improve various symptoms, making patients' daily lives more comfortable.

How to take

Adult dose

For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally, 3 times daily. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability due to acquired lumbar spinal stenosis (patients with normal SLR test results and bilateral intermittent claudication), the usual adult dose is 1 tablet orally, 3 times daily. The dose may be adjusted according to age and symptoms.

Precautions

This medication should not be used in women who are pregnant or may become pregnant. This drug contains lactose, so individuals with a hereditary inability to digest lactose should not take it. Patients with a tendency to bleed or taking medications that may cause bleeding should use this drug with caution. Taking this medication may lead to adverse reactions such as skin rash or itching, so if such symptoms occur, discontinuation should be immediate. Bleeding may occur infrequently, so if signs of bleeding appear, stop taking the drug immediately and consult a doctor. It may affect the digestive system, causing symptoms like diarrhea, nausea, abdominal discomfort, loss of appetite, and heartburn. It may influence liver function, so it is advisable to have regular liver function tests as there is a likelihood of increased liver enzymes. Symptoms such as rapid heartbeat, cold extremities, or low blood pressure may occur, so caution is needed if these symptoms arise. Headaches, flushing of the face, dizziness, a feeling of warmth, and body fatigue may also appear, and if such changes occur, they should be reported. Patients with lumbar spinal canal stenosis should closely monitor changes in symptoms and decide whether to continue taking this medication. Safety during pregnancy is not confirmed, thus individuals who are pregnant must not take it, and uterine contractions have been reported in animal studies. The safety for children has not been established, and therefore, there is no usage experience in this demographic. Elderly individuals may have decreased bodily functions, requiring dosage adjustments and close attention. In healthy adults, administering a high dose may temporarily lower blood pressure, so caution is advised.

Side effects

  • Rash
  • itching
  • bleeding
  • diarrhea
  • nausea
  • abdominal discomfort
  • abdominal pain
  • loss of appetite
  • heartburn
  • vomiting
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  • abdominal bloating
  • elevated AST (GOT)
  • elevated ALT (GPT)
  • palpitations
  • cyanosis of the limbs
  • hypotension
  • headache
  • facial flushing
  • dizziness
  • heat sensation
  • general malaise
  • edema
  • mastitis
  • tremors
  • hypertrichosis
  • anemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a sealed container. It is best to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature. Proper storage will help preserve the drug's efficacy for a longer duration.

Appearance and packaging

Appearance

White round tablet

Package unit

84 tablets (21 tablets/PTP X 4)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.