Celecoxib Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered with or without food. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily or 100 mg twice daily. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily or 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks on 400 mg daily, other treatment options should be considered. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist before use by individuals who consume alcohol daily. Excessive alcohol consumption may cause gastrointestinal bleeding when taking this medication. It may increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke. This risk may increase with higher doses and longer durations of therapy, so it should be used at the minimum effective dose and for the shortest duration necessary. Even in patients without a history of cardiovascular disease, symptoms should be closely monitored, and immediate action should be taken if chest pain, shortness of breath, weakness, or speech difficulties occur. This medication may cause serious adverse reactions such as gastrointestinal perforation, ulcers, or bleeding. Older patients or those with a history of gastrointestinal disorders are at greater risk and should be monitored closely. If symptoms like epigastric pain, dyspepsia, black stools, or hematemesis occur, medical attention should be sought immediately. It should not be administered to patients with a history of specific allergies, severe liver or kidney impairment, active peptic ulcers, heart failure, or to pregnant or nursing women. Patients with compromised liver or kidney function, asthma, hypertension, edema, or the elderly should be observed more closely when using this medication. While taking this medication, adverse effects such as insomnia, dizziness, dyspepsia, headaches, rashes, edema, hypertension, cough, or vomiting may occur. If these symptoms persist or worsen, consult a physician. As this medication is metabolized by the liver, it may alter blood levels when taken with other medications that affect liver function, necessitating dosage adjustments. Women who are pregnant or may become pregnant should not take this medication, as it can harm the fetus during pregnancy, and should stop immediately if they become pregnant while on it. Elderly patients may have reduced kidney and heart function and should be monitored more closely while taking this medication. Patients on prolonged therapy should receive regular blood tests and liver and kidney function tests, and discontinuation should occur if any abnormal findings arise. Dizziness or drowsiness may occur while taking this medication, so it is advisable to avoid driving or operating machinery. This medication does not inhibit platelet aggregation and cannot substitute for aspirin for thromboprophylaxis, and concomitant use with aspirin may increase the risk of gastrointestinal bleeding. While this medication is effective as an anti-inflammatory and analgesic, it does not treat the underlying cause, so it's essential to consult a physician regarding the treatment plan.

Gastrointestinal bleeding, cardiovascular thromboembolic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, muscle tension, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergy exacerbation, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, hearing loss, ear abnormalities, otalgia, hearing impairment, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, jaundice, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic esophagitis, contact dermatitis, injection site reactions, cutaneous nodules, gustatory disorders, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, candidiasis, genital candidiasis, otitis media, mastalgia, menopausal symptoms, fibrocystic changes of the breast, thoracic neoplasms, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and it is best kept in a cool place between 15 and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for a longer period.

Appearance

A white capsule filled with a white to pale yellow powder, marked with a yellow stripe on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle