Adblue Injection

Adult administration

For intravenous administration, adjust the dosage according to the physician's prescription by checking the plasma levels of trace elements. Zinc: 2.5 to 4mg per day Copper: 0.5 to 1.5mg per day Manganese: 0.15 to 0.8mg per day Chromium: 10 to 15㎍ per day For patients receiving non-oral nutritional solutions: 2.5 to 4mg per day (based on zinc) Patients with fluid losses from the small intestine should additionally receive 12.2mg/L (amount of fluid loss) or 17.1mg/kg (amount of feces)

Child administration

Pediatric patients - Under 5 years: 100㎍ per kg of body weight per day (based on zinc) - Infants weighing less than 3kg: 300㎍ per kg of body weight per day Copper: 20㎍ per kg of body weight per day Manganese:

This medication should be diluted before administration, as injecting it directly into the vein without dilution may cause inflammation. This medication is a hypotonic solution and should only be used when mixed with other medications for injection. If any toxic reactions to any component occur during the use of this drug, administration should be discontinued immediately. The amounts of zinc, copper, manganese, and chromium in this drug are very small, so toxic symptoms are unlikely to occur at typical prescribing doses. Prior to administration, the physician must carefully assess the patient's health status and the amount needed by the body. Zinc is primarily excreted through the kidneys, so patients with poor kidney function may accumulate zinc in the body. Copper and manganese are excreted through bile, thus patients with blocked bile flow are at risk of accumulation of these components. Manganese is also excreted through pancreatic juice and can be reabsorbed in various parts of the small intestine. Chromium may affect blood sugar control, so diabetic patients should check their blood sugar status and the diabetes medications they are taking when using this drug. The safety of this drug during pregnancy is not well established, so women who are pregnant or may become pregnant should only use it after consulting a physician and when the benefits of treatment outweigh the risks. In cases of overdose, zinc may cause symptoms such as nausea, vomiting, dehydration, electrolyte imbalance, dizziness, abdominal pain, drowsiness, motor coordination disorders, and in severe cases, may result in death. Copper overdose may lead to symptoms like hypotension, behavioral changes, diarrhea, weight loss, muscle tension reduction, photophobia, and edema, with D-penicillamine being used as an antidote. Information on manganese overdose toxicity is limited, and toxicity from ingestion through food or drink has not been reported. Chromium overdose may lead to nausea, vomiting, ulcers, kidney and liver dysfunction, convulsions, and coma, which are central nervous system disorders. This drug must be used strictly according to a physician's prescription and should not be used arbitrarily without a prescription. When adding this drug to non-oral nutritional solutions, it is advisable to handle it carefully in a laminar flow cabinet to maintain aseptic conditions.

Serious side effects

• Peripheral edema → severe swelling or urination abnormalities
• Liver dysfunction → liver abnormalities (jaundice)
• Convulsions, coma → severe neurological symptoms

Mild side effects

• Nausea
• vomiting
• dehydration
• electrolyte imbalance
• dizziness
• abdominal pain
• drowsiness
• coordination disorders
• hypotension
• behavioral changes

This medication should be stored in a sealed container to prevent air and moisture from entering and should be kept at a temperature between 1 and 30 degrees Celsius (33.8 to 86 degrees Fahrenheit). Storing it this way will help maintain the drug's effectiveness.

Appearance

A light blue transparent liquid contained in a colorless transparent vial.

Package unit

2mL X 10 vials