Crosol Solution (Clobetasol Propionate)

Adult use

Apply an appropriate amount to the affected area 1-2 times daily, adjusting dosage according to symptoms. This medication is a potent corticosteroid, thus continuous treatment exceeding 2 weeks or use of more than 50g (50 mL in solution) in one week is not recommended.

This medication should not be used in patients with skin infections. In particular, the condition may worsen in the presence of bacterial, fungal, viral infections or animal-related skin infections. Moreover, it should not be administered to patients who have had allergic reactions to this medication or its components, patients with perforations in the eardrum suffering from otitis externa, patients with ulcers or severe burns, patients with scalp infections or specific dermatitis, patients with anal and genital itching, and infants under 24 months of age. Caution should be exercised when used in pregnant or potentially pregnant women, nursing mothers, children, the elderly, and patients with liver dysfunction or diabetes. When using this medication, side effects such as skin infections, allergies, or skin irritation may emerge; thus, if symptoms worsen or abnormal reactions occur, use should be immediately discontinued. If used over long periods or on large areas, skin atrophy, vasodilation, rashes, itching, urticaria, and rarely, systemic hormonal changes may occur, necessitating caution. When applying near the eyes, take care to avoid contact directly with the eyes to prevent conditions such as increased intraocular pressure, glaucoma, or cataracts. For pregnant women, using this medication for long durations or large quantities may affect the fetus; thus, use should be limited to minimal duration and area when necessary. Nursing mothers should be cautious as the medication may pass into breast milk, and it is advised to avoid direct application to the nipple or breast area. In children, due to better absorption relative to their weight, there is a higher risk of side effects, thus prolonged use should be avoided, and regular assessment of the condition is required during usage. The elderly are also susceptible to side effects, thus very careful observation is needed for large quantities or prolonged usage. In cases of overdose, signs of adrenal function decrease or hormonal imbalance may occur, and gradual tapering or discontinuation should be done per physician's instructions. This medication should not be applied directly to the eyes and it is advisable not to use it after makeup or shaving; when using a sealed dressing, it should be done according to doctor's instructions. Care should be taken not to exceed treatment areas or to use more than 20% of body surface area, and hands should be washed thoroughly after application. Keep out of reach of children and do not transfer to other containers. Finally, patients with psoriasis should be closely monitored when using this medication in large amounts over long periods, as their psoriasis symptoms may worsen.

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty in breathing, asthma attacks, respiratory abnormalities with cough+fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination issues

Mild side effects

• Folliculitis
• bumps
• skin irritation
• pain
• fever
• burning sensation
• rashes
• erythema
• flushing
• itching

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The optimal storage temperature is between 1 degree and 30 degrees Celsius at room temperature. This way, the medication's effectiveness can be maintained for a longer period.

Appearance

A clear liquid that is uniformly homogeneous

Package unit

50 mL/bottle