Medication info
Esomeprazole Magnesium Trihydrate 20 mg Tablets

Esomeprazole Magnesium Trihydrate 20 mg Tablets

Prescription medicationTablet
Ingredient · strength
Esomeprazole Magnesium Trihydrate›22.3mg / 1 tablet
Manufacturer / importer
위더스제약(주)
Appearance
Light pink round film-coated tablet
Packaging
28 tablets (14 tablets × 2 EA (Alu-Alu))
Approval status
Active

MFDS item code 201500107 · Approved 2015.01.12 · Insurance code 660702750

Summary

Main use
Treatment and prevention of relapses of gastroesophageal reflux disease (erosive reflux esophagitis), treatment of Helicobacter pylori-positive peptic ulcers, etc., for the improvement of gastrointestinal diseases
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquid, such as water, and should not be chewed or crushed. 1. Adults 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. - If untreated or symptoms persist, continue for an additional 4 weeks. - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis:
Children's dosage
Adolescents aged 12 years and older 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. - If untreated or symptoms persist, continue for an additional 4 weeks.

Ingredients

Manufacturer
위더스제약(주)

Efficacy & effects

Treatment and prevention of relapses of gastroesophageal reflux disease (erosive reflux esophagitis), treatment of Helicobacter pylori-positive peptic ulcers, etc., for the improvement of gastrointestinal diseases

  • Gastroesophageal reflux disease
  • erosive reflux esophagitis
  • esophagitis
  • duodenal ulcers positive for Helicobacter pylori
  • peptic ulcers
  • upper gastrointestinal symptoms
  • pain
  • discomfort
  • burning sensation
  • gastric ulcers and duodenal ulcers associated with non-steroidal anti-inflammatory drug treatment
  • Zollinger-Ellison syndrome
  • gastric ulcers
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease, particularly erosive reflux esophagitis, and for long-term maintenance therapy to prevent recurrence in patients with esophagitis. It also helps relieve symptoms of gastroesophageal reflux disease without esophagitis. It is given in combination with antibiotics for the treatment and prevention of recurrence of peptic ulcers caused by Helicobacter pylori infection. It is effective for treating symptoms associated with upper gastrointestinal disturbances that may occur with the use of non-steroidal anti-inflammatory drugs and for the treatment and prevention of related gastric ulcers and duodenal ulcers. Additionally, it is used for the treatment of Zollinger-Ellison syndrome and for maintenance therapy after inducing prevention of re-bleeding via intravenous injection. It is used to improve various gastrointestinal diseases and related symptoms.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquid, such as water, and should not be chewed or crushed. 1. Adults 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. - If untreated or symptoms persist, continue for an additional 4 weeks. - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily. - Treatment of symptoms of gastroesophageal reflux disease without esophagitis:

Children's dosage

Adolescents aged 12 years and older 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. - If untreated or symptoms persist, continue for an additional 4 weeks.

Precautions

This medication should not be administered to certain patients. For example, patients with allergies to this medication or its components, those taking specific antibiotics or medications, and breastfeeding women should not use this medication. While taking this medication, various adverse reactions may occur, requiring caution. Common symptoms may include headache, abdominal pain, and diarrhea, but rarely, serious side effects such as blood abnormalities, skin rashes, and liver dysfunction may also occur. Regular checks should be conducted to monitor health status if this medication is used for a long duration, and immediate consultation with a physician is required if symptoms change. This medication may interact with other drugs, so it is essential to inform healthcare professionals of any co-administered medications. Caution is particularly needed when used in combination with certain antibiotics, antivirals, and blood coagulation medications. Women who are pregnant or breastfeeding should consult a doctor before using this medication, and it is advisable not to take this medication while breastfeeding. In cases of overdose, there is no specific antidote, so it is necessary to visit a medical institution immediately for appropriate treatment. This medication should be kept out of reach of children, and transferring it to another container should be avoided as it may compromise quality.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, anaphylaxis reaction/shock, hypomagnesemia, mental confusion, fever, agranulocytosis, pancytopenia, liver failure, jaundice, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, severe edema, very severe headache, seizures, altered consciousness, visual disturbances

Mild side effects

Headache, dizziness, sensory disturbances, drowsiness, taste disorders, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, myalgia, muscle weakness, interstitial nephritis, gynecomastia, asthenia, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, chest pain, facial swelling, fatigue, fever, leg edema, dizziness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain room temperature between 1 and 30 degrees Celsius. By following these storage guidelines, the effectiveness and safety of the medication can be well preserved.

Appearance and packaging

Appearance

Light pink round film-coated tablet

Package unit

28 tablets (14 tablets × 2 EA (Alu-Alu))

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.