Coxnac Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment at 400 mg per day, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day if needed. From the second day of treatment, the recommended dose as needed is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding in individuals who drink more than three glasses of alcohol regularly, so consultation with a doctor or pharmacist is essential. This medication can affect the cardiovascular system, increasing the risk of thrombosis, myocardial infarction, and stroke; therefore, it should only be used at the minimum effective dose and for a short period. Even individuals without a history of cardiovascular disease should be closely monitored for symptoms. Serious issues such as ulcers, bleeding, and perforation may occur in the gastrointestinal tract, with elderly individuals being at greater risk, so immediate consultation with healthcare professionals is required if symptoms such as epigastric pain, indigestion, black stools, or hematemesis appear. This medication should not be administered to individuals with specific allergy histories, severe liver or kidney disorders, active peptic ulcer disease, heart failure, or to pregnant and breastfeeding women. Patients with decreased liver or kidney function, asthma, hypertension, fluid retention, and the elderly should be closely monitored while taking this medication. Regular liver and kidney function tests should be conducted during treatment, and any abnormal symptoms should be reported immediately. Side effects such as headaches, dizziness, indigestion, skin rashes, and edema may occur. This medication may interact with various other drugs; thus, it is important to inform healthcare providers if taking other medications, especially when combined with antihypertensives, diuretics, anticoagulants, and antidepressants. Pregnant women or those who may become pregnant should not take this medication, and if pregnancy is confirmed during treatment, it should be discontinued immediately. This medication has not been established for safety and efficacy in children and adolescents, so its use is not recommended. Elderly patients may have reduced liver and kidney function, so special care should be taken while using it, and starting at a lower dose is advisable. Dizziness or drowsiness may occur during use, so driving or operating machinery should be avoided. In case of overdose, symptoms such as vomiting, lethargy, and gastrointestinal bleeding may occur, and immediate medical attention should be sought for appropriate treatment. This medication should be kept out of reach of children and should not be transferred to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal tract perforation, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, altered taste, albuminuria, cystitis, hematuria, dysuria, frequency of urination, nephrolithiasis, urinary incontinence, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, positive urinary hematuria, positive urinary protein, renal impairment, acute kidney failure, interstitial nephritis, headache, leg cramps, hypertonicity, sensory decline, migraine, neuralgia, neuropathy, sensory anomaly, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized pustular rash, exfoliative dermatitis, acute kidney failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease nephritis, menstrual disorders, chest pain, anaphylaxis reaction, hallucinations, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is advisable to maintain a storage temperature between 15 and 30 degrees Celsius. This will help to preserve the medication’s efficacy and safety for a longer period.

Appearance

A white capsule filled with powder that is white to light yellow, with yellow stripes on the top and bottom

Package unit

30 capsules/bottle, 100 capsules/bottle