Gasporin Tablet

Adult dose

For adults, the usual dosage is 2 tablets orally twice a day, irrespective of meals, taken in the morning and before bedtime. 1) Gastric and duodenal ulcers: 2 tablets taken twice daily or 4 tablets taken once daily before bedtime. Especially for patients with duodenal ulcers, taking 4 tablets twice daily in the morning and before bedtime can yield higher treatment rates. The dosage is the same for preventive combination therapy for ulcer caused by NSAID use or long-term use of NSAIDs. Usually, diseases caused by NSAID use typically heal within 8 weeks, though healing periods may sometimes be extended depending on the patient. For patients with recurrent ulcers, who showed superior effectiveness during short-term therapy, 2 tablets once daily at bedtime can be administered as maintenance therapy. 2) Gastroesophageal reflux disease: Administer 2 tablets twice daily for 8 weeks, or 4 tablets taken once daily before bedtime. However, for patients with severe gastroesophageal reflux disease, the dosage can be increased to 4 tablets four times a day. 3) Zollinger-Ellison syndrome: Start treatment with an initial dose of 2 tablets three times a day, and the dosage can be increased as necessary. In severe cases, up to 6 g can be given daily as instructed by a physician. 4) Peptic ulcer, acute stress ulcer, and upper gastrointestinal bleeding due to acute gastric mucosal lesions: Once oral administration is possible, switch from injection to oral administration with 2 tablets taken twice daily. 5) Preoperative administration (prevention of Mendelson's syndrome): 2 tablets should be taken 2 hours prior to anesthesia. In this case, taking 2 tablets the night before surgery is also advisable.

This medication should not be used by patients receiving dialysis or those allergic to this drug or its components. It is also advisable to avoid use in patients with a history of acute porphyria, poor kidney function, those who have undergone upper gastrointestinal surgery, pregnant women or those who may become pregnant, premature or newborn infants, and patients on potassium-restricted diets. Patients with impaired liver function or with a history of drug allergies, elderly patients, those with past kidney issues, and those taking NSAIDs should use this drug cautiously. Notably, this medication may mask symptoms of gastric cancer, so patients with gastric ulcers or middle-aged individuals recently experiencing new or changed indigestion symptoms should have malignant status checked before treatment. Patients with gastric or duodenal ulcers due to Helicobacter pylori infection require bacterial eradication treatment. Special precautions are needed for critically ill patients or patients with hypophosphatemia and those with swallowing difficulties while using this medication. This medication can rarely cause allergic reactions such as anaphylactic shock, skin rash, hives, angioedema, fever, bronchospasm, so use should be discontinued immediately if symptoms appear. Blood-related abnormalities like leukopenia, thrombocytopenia, and liver function impairment may occur; if such symptoms arise, stop administration immediately and consult a physician. Neurological symptoms such as heart arrhythmias, gastrointestinal symptoms, dizziness, drowsiness, mental confusion, depression, and hallucinations can also occur rarely, so caution is advised. Side effects such as gynecomastia, erectile dysfunction, arthralgia, myalgia, skin rash, and hair loss have been reported. This medication should not be used for long periods, and treatment progress should be closely monitored while using the minimum effective dose. Elderly patients or those with chronic lung disease or diabetes may face an increased risk of pneumonia, so caution is advised. If dizziness or drowsiness occurs, avoid driving or operating dangerous machinery. This medication may interact with other drugs, so inform medical personnel of any medications being taken, and ensure to separate doses from certain medications. Pregnant or breastfeeding women should avoid this medication, and it is advised not to use it in children as safety and efficacy have not been established. In case of overdose, emergency treatment such as vomiting or gastric lavage may be necessary, and blood dialysis may be required if needed. This drug reduces gastric acid secretion and can promote bacterial growth in the intestines, so ophthalmic examination may be necessary for long-term use.

Serious side effects

• Hives
• angioedema
• bronchospasm
• shock
• anaphylactic shock
• angioedema
• severe allergic reaction
• liver dysfunction
• jaundice
• reversible jaundice hepatitis

Mild side effects

• Skin rash
• fever
• hypotension
• chest pain
• granulocytopenia
• leukopenia
• thrombocytopenia
• elevated serum enzyme levels
• nausea
• vomiting

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is important to store it at room temperature between 1°C and 30°C. Storing it this way will help maintain the drug's effectiveness and prevent deterioration.

Appearance

Green round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle