Nobdepin 5mg Tablet (Amlodipine Besilate)

Adult dose

For adults, 5 mg of amlodipine is taken orally once daily, and the dose may be increased up to a maximum of 10 mg daily depending on the patient's response. Adjust dosage appropriately based on age and symptoms.

This medication should not be used in certain patients. For example, patients who have had an allergic reaction to this drug or others in the same class, nursing women, patients with severe liver dysfunction, those with severe aortic stenosis, and patients in a state of shock should not be administered this medication. Moreover, it should be used cautiously in patients with severe hypotension, those receiving dialysis due to kidney failure, elderly individuals, and women who are pregnant or of childbearing potential. This drug lowers blood pressure and acts on the heart and blood vessels, and the most common side effects include facial flushing, fatigue, swelling of hands and feet, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, a variety of side effects such as hypotension, vasculitis, neurological symptoms, erectile dysfunction, gynecomastia, gastrointestinal issues, elevated blood sugar, myalgia, hair loss, skin rashes, etc. have been reported. Patients with heart failure or severely impaired liver function should be carefully monitored for the effects and side effects of this drug, and blood pressure may change gradually after discontinuation, so caution is advised when using other antihypertensives. This drug can interact with other medications, so it is important to be cautious when taken in combination with specific antibiotics, antihypertensives, hypoglycemic agents, grapefruit juice, etc. It is recommended to avoid grapefruit juice as it may potentiate the effect of the drug. Women who are pregnant or breastfeeding should consult their doctor before using this drug, and it is recommended to discontinue breastfeeding while taking this medication. For children, use is recommended only in those aged 6 years and older, as safety and effectiveness have not been established in children under 6 years. In case of overdose, severe hypotension or cardiac arrhythmias may occur, and immediate medical attention is required with possible emergency treatments like gastric lavage or activated charcoal administration. Lastly, while this medication is known not to significantly affect the ability to drive or operate machinery, individuals may experience dizziness or drowsiness, so caution is advised.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• severe allergic reactions
• severe skin reaction
• yellowing of the skin or eyes (jaundice)
• profound lethargy
• liver abnormalities (jaundice)
• severe edema or urinary disturbances.

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly closed container to prevent exposure to air and moisture. It is best to maintain the storage temperature at room temperature between 1 degree and 30 degrees. This will help to preserve the drug's effectiveness for a longer period.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle