Medication info

Zinc Injection (Zinc Sulfate Hydrate)

Prescription medicationInjections
Ingredient · strength
Zinc Sulfate Hydrate›4.4mg / 1mL
Manufacturer / importer
(주)비씨월드제약
Appearance
A colorless, odorless transparent liquid in a colorless, transparent vial injectable preparation
Packaging
10 milliliters/vial [10mL × 10 vials], 15 milliliters/vial [15mL × 10 vials]
Approval status
Active

MFDS item code 201406139 · Notified 2014.12.30

Summary

Main use
Prevention of zinc deficiency and improvement of nutritional status
Who uses it
Adults · Children
Adult dosage
Metabolically stable TPN patients: 2.5 to 4 mg/day Adults with fluid loss from the small intestine: 12.2 mg/L (amount of fluid loss) or 17.1 mg/kg (excretion rate) additionally Acute burn conditions: 4.5 to 6 mg/day Use as prescribed by a physician, adjusting dosage based on plasma trace element levels.
Children's dosage
Children under 5 years: 100 ug/kg/day Premature infants weighing under 3 kg: 300 ug/kg/day

Ingredients

Manufacturer
(주)비씨월드제약

Efficacy & effects

Prevention of zinc deficiency and improvement of nutritional status

View approved original text

Patients receiving total parenteral nutrition (TPN) require zinc supplementation. This helps prevent zinc deficiency and maintain normal metabolism and immune function. Zinc is essential for wound healing and cell function, so adequate zinc supply during TPN aids in patients' recovery. Therefore, zinc supplementation during TPN is used to improve nutritional status and maintain health.

Dosage and Administration

Adult dosage

Metabolically stable TPN patients: 2.5 to 4 mg/day Adults with fluid loss from the small intestine: 12.2 mg/L (amount of fluid loss) or 17.1 mg/kg (excretion rate) additionally Acute burn conditions: 4.5 to 6 mg/day Use as prescribed by a physician, adjusting dosage based on plasma trace element levels.

Children's dosage

Children under 5 years: 100 ug/kg/day Premature infants weighing under 3 kg: 300 ug/kg/day

Precautions

This medication should not be injected directly into the peripheral vein without dilution. Direct injection may cause phlebitis or zinc toxicity that can damage the kidneys. The amount of zinc in this medication is very low, so toxic symptoms are typically rare. When mixing this medication, it is advisable to work under special equipment called laminar flow to maintain aseptic conditions. Before administration, ensure that there are no precipitates or discoloration in the medication by visual inspection. Administering zinc with copper may decrease copper levels in the blood, so it is necessary to periodically monitor the levels of both components. This medication is excreted through the small intestine and kidneys; therefore, patients with problems in these organs should consider the possibility of zinc accumulation in the body. The safety of this medication has not been established in pregnant women or those who may become pregnant; it should only be administered when the therapeutic benefits outweigh the risks. Zinc can cross the placenta and may be present in breast milk, so pregnant or nursing women should be cautious. Overdose may lead to symptoms such as nausea, vomiting, dehydration, dizziness, and abdominal pain, which can be severe and potentially fatal. Administering calcium together may help prevent some of the toxicity of zinc. Store this medication out of reach of children and in a dry area at room temperature.

Side effects and when to seek care immediately

Mild side effects

  • Nausea
  • vomiting
  • dehydration
  • electrolyte imbalance
  • dizziness
  • abdominal pain
  • drowsiness
  • coordination disorder

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent exposure to air, ideally between 1 and 30 degrees Celsius. Storing it this way can help maintain the medication's effectiveness for a long time.

Appearance and packaging

Appearance

A colorless, odorless transparent liquid in a colorless, transparent vial injectable preparation

Package unit

10 milliliters/vial [10mL × 10 vials], 15 milliliters/vial [15mL × 10 vials]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.