Olmesartan Medoxomil and Amlodipine Tablets 10/40mg (Olmesartan Medoxomil, Amlodipine Besylate)

Adult dose

This medication is administered once daily, one tablet with water, regardless of meals. Taking it at the same time each day (e.g., morning) is recommended. The recommended dosages are as follows: - 5/20mg: Administered to patients whose blood pressure is not adequately controlled with monotherapy of Amlodipine 5mg or Olmesartan Medoxomil 20mg. - 10/20mg: Administered to patients whose blood pressure is not adequately controlled with monotherapy of Olmesartan Medoxomil 20mg.

Child dose

The safety and efficacy in pediatric patients under 18 years of age have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; thus, it should be discontinued immediately upon confirmation of pregnancy. It should not be used by patients who are allergic to this drug's main components or similar medications, pregnant or nursing women, patients with severe liver disease or certain heart conditions, and patients undergoing kidney dialysis. Patients with a deficiency of body fluids or electrolytes should take this medication with caution at the beginning of treatment, as their blood pressure may drop too low. They should seek appropriate treatment immediately if symptoms appear. Patients with severe heart disease, congestive heart failure, or impaired kidney function should use this medication carefully. Side effects such as dizziness, headache, hypotension, swelling, dyspepsia, and others may occur while taking this medication, and any adverse reactions should be reported to a physician immediately. Unlike beta-blockers, this medication should not be discontinued abruptly, and there may be drug interactions when taken with other medications; therefore, consultation with healthcare providers is essential. It is generally advisable not to use this medication during pregnancy, and if planning for pregnancy, switching to safer alternative medications that have been confirmed for safety is recommended. Nursing mothers should consider discontinuing breastfeeding or the medication because it may pass into breast milk. Children under 18 years old should not use this medication, as its safety and efficacy have not been established. Elderly patients may have decreased kidney and liver function; thus, careful monitoring and dosage adjustment are required when taking this medication. In case of overdose, blood pressure may drop excessively, and heart rates may increase, necessitating immediate medical treatment and careful monitoring of blood pressure and heart function. This medication should be kept out of reach of children and stored in a tightly sealed container away from moisture, heat, and direct sunlight; transferring it to another container should be avoided.

Serious side effects

Hives, angioedema, acute renal failure, autoimmune hepatitis, severe allergic reactions, severe skin reactions, dyspnea, jaundice, liver abnormalities, acute renal failure, increased creatinine in the blood, serious neurological symptoms (seizures, confusion, visual disturbances, paralysis), significant decrease in urine output, severe edema, edema accompanied by increased blood pressure, toxic epidermal necrolysis, leukopenia, thrombocytopenia, acute pulmonary edema.

Mild side effects

• Dizziness
• headache
• drowsiness
• sensory disturbances
• reduced sensitivity
• decreased libido
• palpitations
• rapid pulse
• hypotension
• orthostatic hypotension

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is also safe to store at room temperature between 1 degree and 30 degrees Celsius.

Appearance

Brownish-red round film-coated tablets

Package unit

28 tablets/PTP