UnaCare Tablet 5mg (Solifenacin Succinate)

Adult dose

The usual adult dose (including elderly patients) is 5mg once daily as the recommended dose. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment: No dosage adjustment is necessary for patients with mild or moderate renal impairment (creatinine clearance>30mL/min). Use with caution in patients with severe renal impairment (creatinine clearance≤30mL/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment: No dosage adjustment is necessary for patients with mild hepatic impairment. Use with caution in patients with moderate hepatic impairment (Child-Pugh Class B), and do not exceed 5mg once daily. 3. Patients receiving a strong cytochrome P450 3A4 (CYP3A4) inhibitor: For patients receiving ketoconazole or another strong CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in patients with urinary retention, severe gastrointestinal diseases, myasthenia gravis, or angle-closure glaucoma. Additionally, patients undergoing dialysis, those with severe liver or kidney disease, and anyone allergic to this medication or its ingredients should not receive it. Patients at risk for urinary retention or with obstructive gastrointestinal diseases or decreased gastrointestinal motility should use this medication with caution. Patients with severe kidney or liver impairment should take care not to exceed the maximum daily dose, and dosage adjustments may be necessary when used in conjunction with certain potent medications. When using this medication, side effects such as dry mouth, constipation, blurred vision, urinary retention, and dry eyes may frequently occur, so if symptoms are severe, consult a physician. Severe allergic reactions such as angioedema or anaphylaxis may occur, so if these symptoms appear, discontinue use immediately and seek appropriate treatment. Caution is needed when driving or operating machinery due to the risk of drowsiness or blurred vision. Using this medication with other anticholinergic drugs may enhance effects or exacerbate side effects, so caution is advised when combining these medications. Since this drug is metabolized in the liver, dosage adjustments may be necessary in patients with reduced liver function or when taken with certain medications. Pregnant or nursing women should consult a physician before using this medication, and it is especially advisable to avoid it during breastfeeding. Safety and efficacy in pediatric patients have not been established, so it should not be administered to children. In cases of overdose, central nervous system symptoms, blurred vision, dry mouth, and dizziness may occur, and emergency treatment should be obtained immediately. Patients with heart disease or QT prolongation syndrome should consult a physician before use.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• angioedema
• nausea

This medication may be sensitive to air or humidity, so it must be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 and 30 degrees Celsius to preserve the medication's effectiveness and safety for a long time.

Appearance

Bright yellow round film-coated tablet

Package unit

100 tablets/box [(10 tablets/PTPX10)]