Amlodipine Tablets (Amlodipine Besylate)

Adult dose

Administer 5 mg orally once a day as amlodipine, and the dosage may be increased to a maximum of 10 mg per day based on the patient's response. Adjust according to age and symptoms.

This medication should not be used in certain patients. It is contraindicated for individuals with allergies to this medication or similar types of drugs, breastfeeding women, patients with severe liver dysfunction, patients with severe aortic stenosis, and patients in shock. Additionally, it should be administered with caution to patients with severe hypotension, those requiring dialysis due to kidney failure, the elderly, and women who are pregnant or may become pregnant. While taking this medication, side effects such as facial flushing, fatigue, swelling, palpitations, dizziness, headaches, drowsiness, abdominal pain, and nausea may occur. Rarely, various adverse reactions including hypotension, vascular inflammation, neurological abnormalities, dyspepsia, liver dysfunction, and skin rashes have been reported. Patients with heart failure or impaired liver function may be more sensitive to the effects and side effects of this medication. Any abrupt cessation of the medication may lead to gradual changes in blood pressure, so dosage adjustments should be made under a doctor's supervision. This medication is not expected to be effective quickly during emergencies, and it is reported to have little impact on the ability to drive or operate machines. There may be interactions when taken with other medications, so caution is advised especially when taken with certain antibiotics, antihypertensives, analgesics, grapefruit juice, etc. Some medications may increase the plasma concentration of this drug, raising the risk of side effects. For women who are pregnant or breastfeeding, the safety of this medication has not been established, so it should be administered with caution when necessary, and breastfeeding should be discontinued. In children, effectiveness has only been confirmed for those aged 6 and older, and it should not be used in children under 6. In case of overdose, severe hypotension and cardiac issues can occur, necessitating immediate emergency treatment, and this medication cannot be removed by dialysis, so specialized treatment is required. There is no evidence that long-term use of this medication increases the risk of cancer or genetic abnormalities, and it can generally be used safely.

Serious side effects

• Urticaria
• severe swelling (edema)
• jaundice
• toxic epidermal necrolysis
• angioedema
• erythema multiforme.

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headaches
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly closed container to prevent exposure to air or light. Additionally, it is recommended to keep it at room temperature between 1°C and 30°C. This will help maintain the effectiveness of the medication for a longer period.

Appearance

White, octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle