Citrex Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be administered with or without food. ○ Adults: 1) Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2) Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3) Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment at 400 mg per day, consider another treatment option. 4) Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

People who regularly consume more than three glasses of alcohol daily should consult a doctor or pharmacist before taking this medication. Taking this medication while consuming excessive alcohol may increase the risk of gastrointestinal bleeding. This medication may increase the risk of serious cardiovascular events such as thrombotic reactions, myocardial infarction, and stroke. These risks may increase with the dosage and duration of use, so it should only be used at the minimum effective dose for the shortest duration possible. This medication can cause severe gastrointestinal issues such as perforation, ulcers, and bleeding. Careful observation is especially important for the elderly or those with a history of gastrointestinal disorders. If symptoms such as epigastric pain, indigestion, black stools, or vomiting blood occur, immediate consultation with medical personnel is necessary. This medication is not to be administered to individuals with certain allergic reactions, severe liver or kidney dysfunction, pregnant or nursing women, or those with heart disease. Caution is advised when this medication is used in individuals with impaired liver or kidney function, chronic diseases such as asthma, hypertension, heart failure, and diabetes, and regular monitoring may be necessary. During treatment, side effects such as headache, dizziness, indigestion, skin rash, swelling, hypertension, and cough may occur. If symptoms are severe or persistent, consult a doctor. This medication is metabolized in the liver, so interactions may occur when taken with certain drugs. Careful dose adjustment or monitoring is necessary when used in conjunction with drugs that inhibit or induce liver metabolic enzymes. Women who are pregnant or planning to become pregnant should avoid taking this medication, and if pregnancy is confirmed during use, it should be discontinued immediately. Elderly patients may have a higher risk of impaired renal, hepatic, and cardiac function, so they should be observed more carefully while taking this medication. Regular blood tests, liver function tests, and kidney function tests are important to monitor any abnormalities during treatment. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and abdominal pain may occur, and immediate medical attention is necessary for appropriate treatment. This medication should be stored out of the reach of children and should not be transferred to another container for safety.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory disturbance, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, hyposmia, ageusia, allergic reaction, lethargy, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbated bronchospasm, dyspnea, laryngitis, pneumonia, nosebleed, voice disturbances, vesicular dermatitis, dermatitis, nail disease, photosensitive response, pruritus, erythematous rash, maculopapular rash, skin dryness, increased sweating, erythema multiforme, exfoliative dermatitis, mucous membrane syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash with eosinophilia and systemic symptoms, arrhythmia, left ventricular hypertrophy, angina, unstable angina, coronary artery disease, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombophlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, alone, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopause symptoms, fibrocystic disease of the breast, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorder, ovarian cysts, hearing loss, ear abnormalities, ear pain, hearing impairment, abnormal liver function, elevated ALT, elevated AST, increased γ-GTP, elevated ALP, positive urobilinogen, cholecystitis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, elevated serum sodium, elevated serum potassium, increased BUN, CPK elevation, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, elevated alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fracture, tendon rupture, back pain, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, bursitis, contact dermatitis, injection site reaction, nodular dermatitis, gustatory dysfunction, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal arterial or venous occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, photosensitive reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular rash, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease, female infertility, chest pain, lethargy, drowsiness, nausea, upper abdominal pain, gastrointestinal bleeding, hypertension, acute renal failure, respiratory depression, coma

This medication should be stored in a tightly sealed container to prevent air and moisture ingress. It is best to maintain a storage temperature between 15°C and 30°C.

Appearance

A white or light yellow powder contained in a white hard capsule with yellow stripes on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle