Celebrex Capsule 200mg (Celecoxib)

Adult dosage

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be administered with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment at 400 mg per day, consider another treatment option. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication can pose a risk of gastrointestinal bleeding in individuals who regularly consume a certain amount of alcohol daily, and should be discussed with a doctor or pharmacist. Additionally, this medication may increase the risk of cardiovascular thromboembolism, myocardial infarction, and stroke, and these risks may increase depending on the dosage and duration of treatment. If cardiovascular symptoms such as chest pain, shortness of breath, weakness, or slurred speech occur while taking this medication, immediate consultation with medical personnel is necessary. Severe gastrointestinal issues such as ulcers, bleeding, or perforation may occur, and extra caution is needed for the elderly or those with a history of gastrointestinal disease. If symptoms such as epigastric pain, indigestion, black stools, or hematemesis arise, notify medical personnel immediately. This medication should not be administered to individuals with certain allergy histories or severe liver or kidney impairment, active peptic ulcer disease, heart failure, or pregnant women. Patients with impaired liver and kidney functions, asthma, hypertension, or diabetes must undergo careful evaluation before taking this medication, and regular monitoring is recommended. While taking this medication, side effects such as headaches, dizziness, indigestion, vomiting, skin rash, swelling, hypertension, and cough may occur, so immediate consultation with medical personnel is necessary if abnormal symptoms appear. Since this medication is metabolized in the liver, interactions may occur when taken with other medications that affect liver function; therefore, inform a doctor or pharmacist about concomitant medications. It is advisable for pregnant women or breastfeeding mothers not to use this medication, as it may harm the fetus if taken during pregnancy. Elderly individuals are at a higher risk for kidney and heart function decline, requiring careful observation and dosage adjustment. Long-term use of this medication necessitates regular blood tests and assessments of liver and kidney functions, and immediate discontinuation is required if any abnormal findings are observed. In case of overdose, symptoms may include vomiting, drowsiness, lethargy, or gastrointestinal bleeding, necessitating immediate emergency treatment. The safety of this medication has not been established for children and adolescents, so its use is not recommended. Dizziness or drowsiness may occur during treatment, so it is advisable to avoid driving or operating machinery. This medication should be stored in a sealed container to prevent air exposure and kept in a cool place between 15 and 30 degrees Celsius to maintain its efficacy.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforations, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial swelling, influenza-like illness, damage, taste disorder, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbance, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, elevated CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, decreased appetite, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical strain, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in other areas, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, erythema nodosum, contact dermatitis, injection site reaction, skin nodules, headache, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, ageusia, back pain, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, septicemia, sudden death, anaphylaxis-like reactions, angioedema, decreased appetite, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infections, herpes simplex, wound infections, gingivitis, herpes simplex, shingles, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, mastalgia, menopausal symptoms, fibrocystic breast disease, thoracic neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostatic disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug eruption with eosinophilia and systemic symptoms, acute generalized pustular eruption, exfoliative dermatitis, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, female infertility, chest pain, polydipsia, ulcerative stomatitis, gastritis, allergies, low back pain, hyperlipidemia, weight gain

This medication should be stored in a tightly sealed container to prevent air exposure, and kept in a cool place between 15 and 30 degrees Celsius. Proper storage maintains the medication's efficacy.

Appearance

A white or light yellow powder-filled hard capsule with a yellow stripe on the upper and lower parts.

Package unit

30 capsules/bottle, 100 capsules/bottle