Alcoxial 30 mg (Etoricoxib)

Adult dose

Before administering this medicine, consider the potential risks and benefits of this medicine and other alternative treatments. Since the cardiovascular risk increases with higher doses and longer exposure to this medicine, administer it for the shortest possible duration. Adverse reactions such as hypertension, congestive heart failure, and edema may occur during treatment with this medicine. Therefore, at least once a month, regularly reassess whether treatment should be continued based on the patient's symptom relief and response to treatment. This medicine may be administered with or without food. Adults: The recommended dose is 30 mg once daily, and the daily dose should not exceed 30mg. If there is no therapeutic benefit at the recommended dose, discontinue this medicine and consider an appropriate alternative treatment. Patients with hepatic impairment: No dose adjustment is necessary in patients with mild or moderate hepatic impairment (Child-Pugh score 5-9). However, use this medicine with caution in patients with moderate hepatic impairment because experience with its use in these patients is limited. Do not administer this medicine to patients with severe hepatic impairment (Child-Pugh score >9), as there is no experience with its use in these patients. Patients with renal impairment: No dose adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance of 30 mL/min or higher). Do not administer this medicine to patients with severe renal impairment (creatinine clearance below 30 mL/min). Elderly patients: No dose adjustment is necessary in elderly patients.

This medication must be discussed with a doctor or pharmacist before use by individuals who regularly consume more than three alcoholic drinks a day. Drinking heavily while on this medication increases the risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular disease. Serious cardiovascular issues like myocardial infarction and stroke could occur, so patients with heart conditions should be particularly cautious. It is advisable to take the lowest effective dose for the shortest duration possible. It may also affect the gastrointestinal system, potentially leading to severe complications such as bleeding, ulcers, and perforation in the stomach or intestines. These issues can occur without any symptoms, so any occurrence of epigastric pain, indigestion, black stools, or vomiting blood during use requires immediate medical attention. The medication is contraindicated in certain patients. For instance, those who have allergies to this drug or its components, have previously had allergic reactions to aspirin or other nonsteroidal anti-inflammatory drugs, uncontrolled hypertension, heart failure, severe liver or kidney disease, active peptic ulcer, pregnant women or those who could become pregnant, and nursing mothers should not take this medication. Patients with weakened liver, kidney, or heart function, or those with hypertension, diabetes, or asthma should take this medication cautiously and follow medical advice strictly. Regular monitoring of blood pressure, liver function, and kidney function is essential during the course of treatment, and any unusual symptoms should be reported immediately to a healthcare professional. Moreover, this medication may interact with other drugs, so any currently taken medications must be disclosed to a doctor or pharmacist. Caution is especially required when taken with warfarin, ACE inhibitors, diuretics, aspirin, immunosuppressants, some anticancer drugs, and oral contraceptives. Women who are pregnant or planning to become pregnant should consult before taking this medication due to its potential impact on reproductive capacity, and it should not be used during pregnancy. This medication is not recommended for children and adolescents under 18 years of age due to insufficient safety and efficacy data. Older adults may have reduced liver, kidney, or heart function, necessitating even more careful observation when taking this medication. Dizziness and drowsiness may occur during use, caution should be exercised when driving or operating machinery. In cases of overdose, symptoms such as nausea, vomiting, drowsiness, gastrointestinal bleeding, hypertension, and acute kidney failure may appear, so it is important to avoid increasing the dosage or prolonged use without doctor's instructions. Finally, this medication should be stored out of reach of children, and it is safest not to transfer it to another container.

• Gastrointestinal bleeding
• cardiovascular thrombotic reactions
• myocardial infarction
• stroke
• bleeding from the stomach or intestines
• ulcers
• perforation
• osteitis
• gastritis
• upper respiratory infection

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is best to maintain storage temperatures between 1 and 30 degrees Celsius at room temperature. Following this storage method helps to preserve the medication's effectiveness for a longer time.

Appearance

A film-coated tablet shaped like a green apple, convex on both sides, with '101' engraved on one side and 'ACX30' on the other side.

Package unit

30 tablets (10 tablets/PTP x 3 PTP)