Celebrex Capsule 200 milligrams (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be taken with or without food. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily or 100 mg twice daily. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to up to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding in individuals who regularly consume alcohol in excess of a certain amount daily; therefore, consultation with a physician or pharmacist is essential. It may increase the risk of cardiovascular diseases, posing possible serious problems such as heart attack or stroke, so it should only be used at the minimum effective dose and for the shortest duration necessary. Due to the risk of ulcers or bleeding in the gastrointestinal tract, greater caution is needed for individuals with a history of gastrointestinal diseases or the elderly. This medication should not be used in patients with specific allergies or severe liver or kidney impairment, and in women who are pregnant or breastfeeding. Patients with weak liver or kidney function, asthma, hypertension, heart failure, or diabetes should be carefully monitored while using this medication. During treatment, various side effects such as indigestion, abdominal pain, vomiting, dizziness, headaches, skin rashes, etc., may occur, so if any abnormal symptoms appear, immediate consultation with a physician is necessary. There are many interactions with other drugs; special caution is needed when used with medications affecting liver metabolism, antihypertensives, diuretics, anticoagulants, etc., and dose adjustments may be required based on a physician's instructions. Women who are or plan to become pregnant should not take this medication as it may affect the fetus, and breastfeeding mothers should also consult with a professional before use. The safety and efficacy of this medication have not been established for children and adolescents under 18, so it is advisable not to use it. Elderly patients may have decreased liver, kidney, and cardiac functions, requiring more careful monitoring during use. Patients taking this medication long-term should have regular blood tests and liver and kidney function tests to check for abnormalities. Dizziness or drowsiness may occur after use, so it is advisable to avoid driving or operating machinery. In case of overdose, symptoms such as vomiting, lethargy, and gastrointestinal bleeding may occur, necessitating immediate medical attention.

Gastrointestinal bleeding, cardiovascular thromboembolic events, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, hemorrhage, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, pruritus, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, incontinence, urinary tract infection, blurred vision, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, elevated CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, elevated alkaline phosphatase, weight gain, anorexia, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthritis, skeletal malformation, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various areas, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, headache, leg cramps, tension hypertension, sensory decrease, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, tubulointerstitial nephritis, nephrotic syndrome, focal glomerulosclerosis, menstrual disturbances, female infertility, hallucinations, anaphylactic reaction, epistaxis, voice disorders, hearing loss, pneumonia, dyspnea, chest pain

This medication should be stored in a tightly sealed container to prevent air or moisture exposure, at room temperature between 15 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent degradation.

Appearance

A white to slightly yellow powder in a white hard capsule with a yellow stripe on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle