Famotidine 20 mg Tablets

Adult dose

For gastric ulcers, duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, and Zollinger-Ellison syndrome, administer famotidine at a dose of 20 mg orally twice daily (after breakfast, after dinner, or at bedtime) or 40 mg orally once daily (at bedtime). In cases of upper gastrointestinal bleeding, treatment usually starts with injections, transitioning to oral administration once feasible. For improving gastric mucosal lesions (erosion, bleeding, erythema, edema) associated with acute gastritis or acute exacerbation of chronic gastritis: Adults: Administer famotidine at a dose of 10 mg orally twice daily (after breakfast, after dinner, or at bedtime) or 20 mg orally once daily (at bedtime). Adjust dosage appropriately based on age and symptoms.

This medication should not be used in patients who have previously experienced allergic reactions to its components. Patients with a history of allergic reactions to medication or impaired kidney function need to use this medication with caution. In cases of poor kidney function, drug concentration may increase, so dosage should be reduced or dosing intervals should be extended. Patients with heart disease may experience cardiovascular side effects, requiring close observation during administration. Patients with weak liver function should be monitored for worsening symptoms due to potential exacerbation. The elderly may have a higher likelihood of decreased kidney function, which may lead to increased drug concentration; therefore, dosage adjustments may be necessary. Although rare, serious side effects may include allergic shock, blood cell reduction, skin rash, liver dysfunction, muscle damage, heart rhythm abnormalities, consciousness disturbances, nephritis, and pneumonia. If any of these symptoms occur, discontinue use immediately and consult medical personnel. Routine blood tests, liver function tests, and kidney function tests should be performed regularly during treatment and appropriate actions taken if abnormal signs are detected. This medication dissolves in the mouth but is not absorbed through the oral mucosa, so it must be swallowed with water or saliva. Caution is advised if this medication is used alongside phosphate binders during dialysis, as it may reduce the efficacy of calcium carbonate. There may be drug interactions, particularly with certain antifungals or antineoplastics, which may reduce the effectiveness of this medication, so inform healthcare providers about any concurrent medications. Women who are pregnant or may become pregnant should only use it if the benefits of treatment outweigh the risks, and breastfeeding women are advised to discontinue nursing due to the potential for transfer into breast milk. Safety in children has not been sufficiently established, so it should be used cautiously in this population. Lastly, this medication may mask symptoms of gastric cancer, so it is important to confirm that the condition is not gastric cancer before using it.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reaction
• Severe rash with high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes → severe skin adverse reaction
• Shortness of breath or difficulty breathing, asthma attacks, cough + fever accompanied by respiratory issues → respiratory problems
• Yellowing of skin or eyes (jaundice), profound lethargy → liver abnormalities (jaundice)
• Sudden and

Mild side effects

• Hypersensitivity
• rash
• hives
• facial swelling
• constipation
• diarrhea
• dry mouth
• nausea
• vomiting
• abdominal bloating

This medication should be stored in a tightly closed container to avoid contact with air and at room temperature between 1°C and 30°C. Proper storage maintains the medication's effectiveness and prevents degradation.

Appearance

White to off-white round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle