UCox Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered with or without food. Adults: Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg per dose twice daily in divided doses. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg per dose twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg per dose twice daily in divided doses. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication increases the risk of gastrointestinal bleeding in people who consume a lot of alcohol daily, so it should be taken only after consulting a doctor or pharmacist. If there are problems with the heart or blood vessels or risk factors exist, this medication can lead to cardiovascular issues such as thrombosis, myocardial infarction, and stroke, so it should be used at the minimum effective dose and for the shortest duration possible. Patients with a history of gastric ulcers or bleeding should be especially cautious when taking this medication due to the increased risk of gastric perforation, ulcers, and bleeding; if abnormal symptoms occur, they should immediately visit a hospital. This medication is not administered to patients with certain allergies, severe liver or kidney dysfunction, pregnant or nursing women, or patients with certain heart diseases. Patients with impaired liver or kidney function, hypertension, heart failure, asthma, diabetes, etc., should be monitored more closely while using this medication. This medication can cause various side effects including dyspepsia, headache, dizziness, skin rash, swelling, and heart problems, so any abnormal symptoms should be reported to healthcare staff immediately. Regular blood tests and liver and kidney function tests are required with long-term use, and medications may need to be discontinued if there are abnormal findings. This medication has many drug interactions, so it is essential to inform about any current medications, especially when combined with antihypertensives, anticoagulants, antidepressants, and anticancer agents. Pregnant women or those planning to become pregnant should avoid taking this medication, and it is also advisable for nursing mothers not to take this medication. The safety and efficacy for children or adolescents have not been established, so it is not to be used in those populations. Elderly individuals may have a higher risk of impaired kidney, liver, and heart functions, requiring special monitoring while taking this medication. This medication may cause drowsiness or dizziness during driving or operating machinery, so caution is advised. In case of overdose, symptoms may include nausea, vomiting, drowsiness, and gastrointestinal bleeding, and immediate medical treatment should be sought.

Gastrointestinal bleeding, cardiovascular thromboembolic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforations, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, hot flashes, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequent urination, kidney stones, urinary incontinence, urinary tract infection, visual confusion, cataracts, conjunctivitis, eye pain, glaucoma, intraocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, elevated BUN, elevated CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, synovial cysts, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in the back and other areas, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, pyoderma, contact dermatitis, injection site reactions, skin nodules, headache, leg cramps, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, generalized edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitive reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular rashes, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, anaphylaxis, hallucinations, vasculitis, pulmonary embolism, gastrointestinal bleeding, hepatitis

This medication should be stored in a sealed container to prevent air or moisture from entering, ideally in a cool place between 15 and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness and prevents degradation.

Appearance

White or pale yellow powder filled hard capsule with a yellow striped white color.

Package unit

30 capsules (10 capsules/PTP packaging x 3), 100 capsules/bottle