Disalin Capsule (Diacerein)

Adult dose

Adults: Administer 50∼100mg of diacerein orally in 1∼2 divided doses after meals. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used by patients with inflammatory bowel disease or those with intestinal obstruction syndrome. Patients with unexplained abdominal pain should also refrain from taking this medication. Individuals allergic to this medication, its components, or Rhein-class drugs should avoid taking it. Those with liver disease or a history of liver disease are advised not to use this medication. Children under 15 years of age should not take this medication. Additionally, this medication contains lactose, so individuals with lactose intolerance or related genetic disorders should avoid taking it. Patients with a history of small intestine or colon disease should use this medication cautiously. Pregnant or breastfeeding women should also exercise caution when using this medication. Elderly individuals over 65 years of age should reduce the dosage of this medication. People who are allergic or sensitive to the ingredient Yellow No. 5 included in this medication should use it carefully. This medication can sometimes cause gastrointestinal symptoms such as diarrhea, loose stools, and abdominal pain. Prolonged use may lead to serious side effects such as gastrointestinal bleeding, ulcers, or perforations, so caution is necessary. If diarrhea worsens, dehydration and electrolyte imbalance may occur, so immediate cessation of use and consultation with a physician is required. Skin symptoms such as itching, rash, and eczema may commonly occur. It may also affect liver function, with increased liver enzyme levels possible. When taking this medication long-term, it is essential to follow the physician's instructions. If diarrhea occurs, there is a risk of dehydration and hypokalemia, so stop taking it and follow the physician's instructions. It is advisable to avoid taking laxatives together. If signs of liver damage appear, immediately stop taking the medication and consult a physician, and it is also recommended to limit alcohol intake. This medication should be taken with at least a 2-hour interval from antacids or salts that contain calcium, magnesium, or aluminum to avoid decreased absorption. Taking it with diuretics may increase diuretic effects and pose a risk of dehydration and hypokalemia, so caution is necessary. There is a risk of arrhythmia when taken with cardiac glycosides, requiring careful monitoring. Pregnant or breastfeeding women are advised not to take this medication. Animal studies have reported delayed bone formation in fetuses, and there is insufficient safety data for humans. The components of this medication may be transmitted to the baby through breast milk, so it should be avoided during breastfeeding. In case of overdose, severe diarrhea may occur, and necessary treatment such as electrolyte supplementation should be administered.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, dehydration, fluid and electrolyte imbalance, itching, rash, eczema, elevated liver enzymes in serum

This medication may be sensitive to air and moisture, so it must be stored in a tightly closed container. The storage temperature should be maintained between 1 and 30 degrees Celsius (room temperature). This will help preserve the medication's efficacy and safety for a long time.

Appearance

A hard capsule with an upper yellow and a lower light yellow color containing a brownish powder.

Package unit

30 capsules/bottle, 300 capsules/bottle