Solshin 5 mg (Solipecan Sodium Succinate)

Adult dose

The usual recommended dose for adults (including older adults) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment: No dosage adjustment is necessary for patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use with caution in patients with severe renal impairment (creatinine clearance≤30ml/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment: No dosage adjustment is necessary for patients with mild hepatic impairment. Use with caution in patients with moderate hepatic impairment (Child-Pugh Class B), and do not exceed 5mg once daily. 3. Patients taking potent cytochrome P450 3A4 (CYP3A4) inhibitors: Limit the maximum daily dose to 5mg in patients taking ketoconazole or another potent CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole).

This medication is used to manage the overactive response of the bladder. It should not be used in patients with symptoms of urinary retention, severe gastrointestinal disorders, myasthenia gravis, glaucoma, or known allergies to the medication. Patients undergoing hemodialysis or those with severe liver or kidney dysfunction should also avoid this medication. It should be used with caution in individuals with urinary outlet obstruction, reduced gastrointestinal motility, moderate liver or kidney dysfunction, or those taking certain other medications. Side effects may include dry mouth, constipation, blurred vision, urinary retention, dry eyes, lower limb edema, fatigue, cough, hypertension, nausea, dyspepsia, abdominal pain, vomiting, influenza, pharyngitis, dizziness, depression, difficulty urinating, decreased urinary flow rate, bladder grip, urinary tract infection, cystitis, nasopharyngitis, vomiting, gastroesophageal reflux disease, intestinal obstruction, peripheral edema, headache, hallucinations, drowsiness, delirium, renal dysfunction, itching, rash, angioedema, erythema multiforme, exfoliative dermatitis, and heart symptoms. Serious side effects such as gastrointestinal obstruction have been rarely reported, especially at high doses. If severe allergic reactions such as angioedema or anaphylaxis occur, the medication should be discontinued immediately and medical attention sought. This medication can occasionally cause drowsiness, fatigue, or blurred vision, so caution is advised when driving or operating machinery. Additionally, this medication is metabolized in the liver by a specific enzyme (CYP3A4); concomitant use with drugs that strongly inhibit this enzyme may increase drug concentration and the risk of side effects. Pregnant or nursing women should consult a doctor before taking this medication, and it should not be used in children as safety and effectiveness have not been established. In cases of overdose, symptoms may include headache, dizziness, drowsiness, and blurred vision, and gastric lavage or detoxification treatment may be needed. Before taking this medication, inform your doctor of any other diseases or medications you are taking, and ensure regular check-ups for safe use.

• dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• vascular allergic edema
• nausea

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Bright yellow round film-coated tablet

Package unit

100 tablets (10 tablets/PTP*10)