Medication info
Bupropion Tablets (Bupropion Hydrochloride)

Bupropion Tablets (Bupropion Hydrochloride)

Prescription medicationTablet
Ingredient · strength
Bupropion Hydrochloride›100mg / 1 tablet
Manufacturer / importer
Albotec Korea Co., Ltd.
Appearance
Pink round film-coated tablet
Packaging
100 tablets (10 tablets/PTP x 10)
Approval status
Active

MFDS item code 201405262 · Approved 2014.11.11

Summary

Main use
Treatment of depression
Who uses it
Adults
Adult dosage
Adults: As with other antidepressants, treatment should continue for at least 4 weeks. Administer 100㎎ per dose 3 times daily. Initially, administer 100㎎ per dose twice daily, and, depending on the clinical response, increase to 100㎎ per dose 3 times daily after at least 4 days. General administration: It is important to minimize the risk of seizures. During dose increases, do not increase the total daily dose by more than 100㎎ in 3 days. During gradual dose escalation, it is important to monitor for and minimize the frequent occurrence of agitation, ataxia, and insomnia early in treatment. If necessary, these may be managed with a temporary dose reduction or temporary administration of an intermediate- or long-acting sedative-hypnotic. A sedative-hypnotic is not needed during the first week of treatment; insomnia can be minimized by avoiding administration at bedtime. If adverse effects occur, stop increasing the dose. Do not exceed 150mg per dose. Administer 3 times daily at intervals of at least 6 hours. When administering more than 300mg daily: If there is no clinical response after treatment with 300mg daily for several weeks, the dose may be increased to a maximum of 450mg daily, up to 150mg per dose. To ensure that no single dose exceeds 150mg, administer 100mg per dose 4 times daily at 4-hour intervals. Discontinue this medicine if an adequate response is not achieved with 450mg daily. Maintenance therapy: The lowest dose is recommended. The duration of treatment is unknown, but is generally considered to be several months or longer, as needed for acute treatment of depression.

Ingredients

Manufacturer
Albotec Korea Co., Ltd.

Efficacy & effects

Treatment of depression

  • Depression
View approved original text

This medication is used to alleviate symptoms of depression and improve mood.

Dosage and Administration

Adult dosage

Adults: As with other antidepressants, treatment should continue for at least 4 weeks. Administer 100㎎ per dose 3 times daily. Initially, administer 100㎎ per dose twice daily, and, depending on the clinical response, increase to 100㎎ per dose 3 times daily after at least 4 days. General administration: It is important to minimize the risk of seizures. During dose increases, do not increase the total daily dose by more than 100㎎ in 3 days. During gradual dose escalation, it is important to monitor for and minimize the frequent occurrence of agitation, ataxia, and insomnia early in treatment. If necessary, these may be managed with a temporary dose reduction or temporary administration of an intermediate- or long-acting sedative-hypnotic. A sedative-hypnotic is not needed during the first week of treatment; insomnia can be minimized by avoiding administration at bedtime. If adverse effects occur, stop increasing the dose. Do not exceed 150mg per dose. Administer 3 times daily at intervals of at least 6 hours. When administering more than 300mg daily: If there is no clinical response after treatment with 300mg daily for several weeks, the dose may be increased to a maximum of 450mg daily, up to 150mg per dose. To ensure that no single dose exceeds 150mg, administer 100mg per dose 4 times daily at 4-hour intervals. Discontinue this medicine if an adequate response is not achieved with 450mg daily. Maintenance therapy: The lowest dose is recommended. The duration of treatment is unknown, but is generally considered to be several months or longer, as needed for acute treatment of depression.

Precautions

This medication is primarily used for the treatment of depression. When taking this medication, there is an increased risk of suicidal thoughts or behavior, so young patients, particularly those aged 18 to 24, should be monitored closely. Additionally, this medication should not be taken in conjunction with other medications that contain the same ingredient. This medication has the potential to induce seizures, and dosage should be adjusted, as it should not be administered to patients with a history of seizures. Patients with poor liver function or cirrhosis should reduce the dosage and use this medication with caution. During treatment, side effects may include agitation, insomnia, headache, nausea, constipation, etc. If there are changes in psychiatric symptoms or suicidal tendencies, consult a physician immediately. Women who are pregnant or nursing should discuss the use of this medication with their doctor before starting, and it is advisable to avoid using it while nursing if possible. Elderly patients or those with reduced kidney function may also require dose adjustment. Overdosage can lead to serious side effects, so it is crucial to adhere strictly to the prescribed dosage. Additionally, this medication can interact with other drugs, so if you are taking other medications, you should inform your doctor or pharmacist. Caution is advised when driving or operating machinery, and it is best to avoid alcohol consumption. Finally, this medication is not recommended for children and adolescents.

Side effects

Suicidal ideation, suicidal tendencies, agitation, dry mouth, insomnia, headache, migraine, nausea, vomiting, constipation, tremor, neuropsychiatric disturbances, seizures, skin rash, itching, angioedema, shortness of breath, erythema multiforme, Stevens-Johnson syndrome, anaphylactic shock, arthralgia, myalgia, fever, delayed hypersensitivity reaction, edema, deep vein issues, dizziness, hypertension, hypotension, palpitations, fainting, tachycardia, loss of appetite, increased appetite, diarrhea, dyspepsia, weight gain, weight loss, erectile dysfunction, menstrual discomfort, frequent urination, urinary retention, akathisia, inability to exercise, exercise inertia, skin temperature disturbances, excessive sweating, decreased sleep quality, increased salivation, muscle spasms, pseudo-Parkinsonism, sedation, sensory disturbance, anxiety, confusion, decreased libido, delusions, concentration impairment, abnormal happiness, hostility, fatigue, fever, upper respiratory discomfort, hearing impairment, visual impairment, taste disturbance, coordination failure, tonic-clonic muscle spasms, movement disorders, dystonia, mydriasis, vertigo, speech disturbance, EEG abnormalities, neurological examination abnormalities, attention deficits, sciatica, aphasia, mania, hypomania, increased libido, hallucinations, sexual dysfunction, depression, memory impairment, depersonalization, psychosis, dysphoria, mood instability, paranoia, formal thought disorder, cold sensation disorder, increased suicidal tendencies, suicidal impulses, gastritis, stomatitis, toothache, bruxism, gum irritation, oral edema, glossitis, bronchitis, shortness of breath, nosebleed, respiratory rate and rhythm disorders, pneumonia, pulmonary embolism, visual impairment, diplopia, cold symptoms, nonspecific pain, body odor, surgical pain, infection, drug reactions, overdose, arthralgia, myalgia, fever with rash, delayed hypersensitivity reaction, hypertension, orthostatic hypotension, third-degree heart block, inappropriate antidiuretic hormone secretion, hyperglycemia, hypoglycemia, esophagitis, hepatitis, liver damage, jaundice, lymph node disorders, anemia, pancytopenia, musculoskeletal chest pain, aggression, coma, delirium, abnormal dreams, obsessive ideas, sensory abnormalities, restlessness, delayed onset movement disorder, Stevens-Johnson syndrome, angioedema, exfoliative dermatitis, urticaria, tinnitus, increased intraocular pressure, fever, muscle cramps, rhabdomyolysis, hypotension, confusion, drowsiness, loss of consciousness, coma, respiratory failure, arrhythmia, QRS prolongation, blurred vision, dizziness, confusion, nausea, anxiety, visual hallucinations, staggering, hallucinations, loss of consciousness, homocentric tachycardia, fever, muscle rigidity, rhabdomyolysis, sensory paralysis, coma, respiratory system failure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a special container that does not allow light in. Additionally, it is important to store it at a cool temperature below 25 degrees Celsius to maintain its efficacy.

Appearance and packaging

Appearance

Pink round film-coated tablet

Package unit

100 tablets (10 tablets/PTP x 10)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.