Cerepacapsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg per dose twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks at 400 mg daily, consider other treatment options. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day onward, the recommended dose as needed is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), reduce the dose to approximately 50% of the recommended daily dose.

This drug should be consulted with a doctor or pharmacist before taking by individuals who consume large amounts of alcohol daily; otherwise, gastric bleeding may occur. This drug can increase the risk of cardiovascular diseases such as heart attacks or strokes; therefore, it should be taken at the minimum possible dose and for the shortest duration possible. Cardiovascular disease symptoms should be carefully monitored during treatment. This drug can cause serious problems like ulcers or bleeding in the stomach. Older individuals are at higher risk for these side effects, so symptoms such as epigastric pain, indigestion, black stools, and hematemesis should be carefully observed during treatment. This drug should not be given to specific allergy patients, patients with severe liver or renal dysfunction, heart patients, pregnant or nursing women, or children. Patients with weakened liver or kidney function, asthmatic patients, hypertensive patients, heart failure patients, etc., should be especially cautious when using this drug and should undergo regular examinations as per doctor’s instructions. This drug can cause various side effects, with common symptoms including indigestion, diarrhea, headache, dizziness, hypertension, rash, etc. If severe skin rash or breathing difficulties occur, immediate consultation with healthcare personnel is necessary. This drug may interact with other medications; therefore, patients must inform their doctors about any other medications being taken, particularly when taken with antihypertensives, diuretics, anticoagulants, antidepressants, etc. Women who are pregnant or may become pregnant should avoid using this drug, and if pregnancy is confirmed during treatment, it should be stopped immediately. Additionally, this drug can also be transferred through breast milk, so nursing women should also avoid taking it. The safety and efficacy of this drug in children and adolescents under 18 years have not been established, so it is advisable not to use it in this population. Because the elderly may have decreased renal and liver functions, special caution is required when taking this drug, and dosages may need to be adjusted. If this drug is taken over a long period, regular blood tests and checks on liver and kidney functions should be performed, and if abnormal signs are discovered, immediate consultation with a doctor is necessary. Overdose may cause symptoms such as nausea, vomiting, drowsiness, and lethargy, and in severe cases, gastric bleeding or worsening renal function may occur, so an immediate visit to a medical institution is required. This drug should be kept out of the reach of children, and transferring it to another container is not recommended for quality maintenance.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle tone increase, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disorder, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, visual clouding, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased NAG, positive urine blood, positive urine protein, renal dysfunction, acute kidney injury, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, decreased appetite, elevated LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various locations, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, bile stasis, bile stasis hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute kidney injury, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, female infertility, hallucinations, nosebleeds, hearing loss, thirst, ulcerative stomatitis, gastritis, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, RA factor positive, herpes zoster, pneumonia, dyspnea

This medication should be stored in a tightly sealed container to keep out air and moisture and should be kept in a cool place between 15 to 30 degrees.

Appearance

Hard capsule filled with white to light yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle