Medication info
Donecett 10mg (Donepezil Hydrochloride Monohydrate)

Donecett 10mg (Donepezil Hydrochloride Monohydrate)

Prescription medicationTablet경구
Ingredient · strength
Donepezil Hydrochloride Hydrate›10.43mg / 1 tablet
Manufacturer / importer
(주)킵스바이오파마
Appearance
Yellow round film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 201405224 · Approved 2014.11.07 · Insurance code 693201260

Summary

Main use
Improvement of symptoms of Alzheimer's disease
Who takes it
Adults · Children
Adult dose
As Donepezil Hydrochloride, administer 5 mg once daily at bedtime. After 4 to 6 weeks of administration at the 5 mg dose, evaluate the clinical response and potentially increase to 10 mg. In cases where the dosage is increased to 10 mg daily, monitor for gastrointestinal adverse reactions during administration. Underweight female patients aged 85 and older should not exceed 5 mg daily.
Child dose
There is no experience using this medication in children.

Ingredients

Manufacturer
(주)킵스바이오파마

Efficacy & effects

Improvement of symptoms of Alzheimer's disease

  • Symptoms of Alzheimer's disease
View approved original text

This medication is used in the treatment of symptoms of Alzheimer's disease and helps improve memory decline and cognitive function. This can lead to enhancements in daily functioning and quality of life. It also helps to slow the progression of symptoms, thereby reducing the burden on patients and their families. This drug is effective in alleviating dementia symptoms and supporting cognitive function in patients. Overall, it is used to treat the symptoms of Alzheimer's disease.

How to take

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily at bedtime. After 4 to 6 weeks of administration at the 5 mg dose, evaluate the clinical response and potentially increase to 10 mg. In cases where the dosage is increased to 10 mg daily, monitor for gastrointestinal adverse reactions during administration. Underweight female patients aged 85 and older should not exceed 5 mg daily.

Child dose

There is no experience using this medication in children.

Precautions

This medication should not be used by individuals allergic to certain ingredients, pregnant or breastfeeding women, or those with hereditary issues such as lactose intolerance. Patients with heart conditions or heart rhythm issues should use this medication with caution, as it may cause arrhythmias or bradycardia. Individuals with a history of gastric ulcers or peptic ulcers, or those taking non-steroidal anti-inflammatory drugs should be careful due to the risk of gastrointestinal bleeding or exacerbation of ulcers. Patients with asthma or obstructive pulmonary diseases should be cautious as bronchoconstriction and increased mucus production can worsen symptoms. Patients with extrapyramidal disorders such as Parkinson's disease should use this medication carefully as it may worsen symptoms. This medication can cause serious side effects including fainting, heart block, gastrointestinal bleeding, liver dysfunction, cerebrovascular issues, movement disorders, acute pancreatitis, and renal failure; any unusual symptoms should be reported to healthcare providers immediately. Common side effects can include dizziness, nausea, vomiting, diarrhea, insomnia, headache, and fatigue; it is important to monitor for these effects. Patients with heart disease or a history of QT interval prolongation should have their condition checked periodically through ECG. This medication can affect driving or machine operation capabilities, so caution is needed early in treatment or during dose increases. Interactions with other medications are possible, so it is essential to inform healthcare providers about any other medications being taken, particularly cardiac drugs, antibiotics, antidepressants, and antipsychotics. Pregnant or breastfeeding women should not use this medication unless it is absolutely necessary and should consult with a specialist beforehand. In case of overdose, serious symptoms such as nausea, vomiting, bradycardia, hypotension, and respiratory depression may occur; strict adherence to the prescribed dosage is required, and any overdose should be treated by healthcare professionals immediately. The safety of this medication has not been established in children, so it is advisable not to use it in pediatric patients. This drug should be stored in a tightly closed container to protect it from air and kept at room temperature between 1 and 30 degrees to maintain its effectiveness and prevent degradation.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, difficulty or shortness of breath, asthma attacks, respiratory irregularities accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headaches, thunderclap headaches, seizures, disorientation, visual disturbances, paralysis, urination

Mild side effects

Nausea, vomiting, diarrhea, loss of appetite, headache, fatigue, fever, insomnia, dizziness, tremors, urinary incontinence, changes in blood pressure (hypertension, hypotension), myalgia, cold symptoms, itching, rash, drowsiness, anxiety, hallucinations, aggressive behavior, gait disturbances, involuntary movements, decreased concentration, mental dullness, weakness, sweating, thrombocytopenia, anemia, leukopenia, dehydration, urticaria, facial swelling, lethargy, skin ulcers, psoriasis, skin discoloration,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air exposure, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the drug's effectiveness and prevents degradation.

Appearance and packaging

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.